Hill C A, Hunter J V, Moseley I F, Kendall B E
Lysholm Department of Radiology, National Hospital for Neurology and Neurosurgery, London, UK.
Br J Radiol. 1992 Dec;65(780):1105-7. doi: 10.1259/0007-1285-65-780-1105.
Although there is a substantial body of evidence implicating Myodil or Pantopaque as a cause of lumbar arachnoiditis, assessment of the clinically based evidence is complicated by the additional potentially causative factors present in a high proportion of cases. These include pre-existing spinal pathology, traumatic lumbar puncture and surgery. The aim of this retrospective study was to attempt to ascertain whether Myodil introduced via ventricular catheter was associated with subsequent development of symptomatic lumbar arachnoiditis. In 222 patients in whom clinical records were reviewed there was no excess of back pain following ventriculography compared to the general population. Myodil ventriculography does not appear to be a major cause of symptomatic lumbar arachnoiditis. Several unavoidable problems with the methodology of this study are discussed.
尽管有大量证据表明碘苯酯或泛影葡胺是导致腰骶部蛛网膜炎的原因，但对基于临床的证据进行评估时，因在很大比例的病例中存在其他潜在致病因素而变得复杂。这些因素包括既往存在的脊柱病变、创伤性腰椎穿刺和手术。这项回顾性研究的目的是试图确定经脑室导管注入的碘苯酯是否与随后症状性腰骶部蛛网膜炎的发生有关。在222例经查阅临床记录的患者中，与普通人群相比，脑室造影术后背痛并未增多。脑室碘苯酯造影似乎不是症状性腰骶部蛛网膜炎的主要原因。本文讨论了该研究方法中几个不可避免的问题。
