Advances in management of retinoblastoma.

Retinoblastoma is a highly malignant intraocular tumor of children that requires accurate diagnosis to prompt treatment. This article reviewed clinical, pathological and follow-up data on 1 147 cases of retinoblastoma registered in Japan from 1975 to 1982. It is obvious that the prognosis of children with retinoblastoma has improved remarkably in recent years. The current advances in the management of the retinoblastoma were discussed.