Vernon S A, Quigley H A
Academic Unit of Ophthalmology, University Hospital, Nottingham, UK.
Eye (Lond). 1992;6 ( Pt 5):521-4. doi: 10.1038/eye.1992.110.
In order to determine the loss of retinal sensitivity detectable by oculokinetic perimetry (OKP), we tested 27 eyes of 27 persons with glaucoma and 32 eyes of 32 patients with ocular hypertension with the OKP screener and with a central threshold test on the Humphrey analyser. The threshold at eight locations on the OKP chart between 12.5 degrees and 15 degrees from fixation was compared with the corresponding Humphrey perimetric thresholds. Seventeen eyes from 17 patients with glaucoma failed the OKP screening test by not seeing the target at one or more locations. The mean light sensitivity threshold at points seen on OKP screening was -5.8 dB (SD 4.6 dB) from aged-matched normals (AMN), whereas points missed had a mean threshold -16.1 dB (SD 9.3 dB) from AMN. The sensitivity and specificity with which OKP testing differentiated normal points from abnormal ones in Humphrey testing was 82.5% and 80% respectively, with a threshold criterion of -12 dB from AMN. Ten eyes from 10 patients with glaucomatous defects and all of the ocular hypertensive eyes gave normal responses on the OKP screening test. The glaucomatous eyes that passed were characterized by less severe defects on the Humphrey than those who failed in terms of mean deviation (0.02 < p < 0.05) or corrected pattern standard deviation (0.01 < p < 0.02). Four of the glaucomatous eyes to pass had a nasal step as the primary field defect. None of those to fail failed only on points within 10 degrees of fixation. We suggest further modification of the OKP screening chart to improve its efficiency.
为了确定眼动视野计（OKP）可检测到的视网膜敏感性损失，我们使用OKP筛查仪以及Humphrey分析仪的中心阈值测试，对27例青光眼患者的27只眼和32例高眼压症患者的32只眼进行了检测。将OKP图表上距注视点12.5度至15度之间八个位置的阈值与相应的Humphrey视野阈值进行比较。17例青光眼患者的17只眼中，有一只或多只眼睛在一个或多个位置未看到目标，从而未通过OKP筛查测试。在OKP筛查中看到光点处的平均光敏感度阈值与年龄匹配的正常眼（AMN）相比为-5.8 dB（标准差4.6 dB），而未看到的光点平均阈值与AMN相比为-16.1 dB（标准差9.3 dB）。在Humphrey测试中，以与AMN相差-12 dB为阈值标准，OKP测试区分正常点与异常点的敏感性和特异性分别为82.5%和80%。10例有青光眼性缺损的患者的10只眼以及所有高眼压症患者的眼睛在OKP筛查测试中均给出正常反应。通过测试的青光眼性眼睛在Humphrey视野测试中的特征是，与未通过的眼睛相比，其平均偏差（0.02 < p < 0.05）或校正模式标准差（0.01 < p < 0.02）方面的缺损较轻。4只通过测试的青光眼性眼睛以鼻侧阶梯作为主要视野缺损。未通过测试的眼睛均不是仅在距注视点10度以内的位置未通过。我们建议进一步修改OKP筛查图表以提高其效率。
