Mitch William A, Gerecke Andreas C, Sedlak David L
Department of Civil and Environmental Engineering, University of California, 609 Davis Hall, Berkeley, CA 94720, USA.
Water Res. 2003 Sep;37(15):3733-41. doi: 10.1016/S0043-1354(03)00289-6.
N-nitrosodimethylamine (NDMA) is a potent carcinogen formed during chloramination of water and wastewater treatment plant effluents. A procedure is described for quantifying the concentration of the organic precursors of NDMA that could be formed during chlorination of wastewaters and natural waters. The method involves applying a high dose of monochloramine to a pH-buffered sample followed by a 10-day contact period, during which the monochloramine decays at a rate unrelated to the composition of the sample. Analyses of samples of municipal wastewater effluents and surface waters indicate that the method provides a robust and reproducible measurement of NDMA precursors over a wide range of conditions. A sensitive GC/CI/MS/MS analytical procedure for dimethylamine also is described and used to demonstrate that NDMA formation during chlorination of wastewater and natural waters cannot be explained by dimethylamine concentrations alone.
N-亚硝基二甲胺（NDMA）是在水和污水处理厂废水的氯胺化过程中形成的一种强效致癌物。本文描述了一种用于量化在废水和天然水氯化过程中可能形成的NDMA有机前体浓度的方法。该方法包括向pH缓冲的样品中加入高剂量的一氯胺，然后进行10天的接触期，在此期间一氯胺以与样品组成无关的速率衰减。对城市污水厂出水和地表水样品的分析表明，该方法在广泛的条件下能够对NDMA前体进行可靠且可重复的测量。本文还描述了一种用于二甲胺的灵敏的气相色谱/化学电离/串联质谱分析方法，并用于证明废水和天然水氯化过程中NDMA的形成不能仅用二甲胺浓度来解释。
