Stewart Jesse C, France Christopher R, Sheffield David
Ohio University, Athens, 45701, USA.
Ann Behav Med. 2003 Aug;26(1):8-14. doi: 10.1207/S15324796ABM2601_02.
For this study we investigated the relationship between hypertension, pain reports, and hypertension awareness in a large and diverse sample of men and women.
Data collected during the Third National Health and Nutrition Examination Survey (NHANES III) were examined for reports of pain at four body sites (chest, back, legs, and gallbladder) in 9,427 adults. Respondents were classified into four groups based on their self-reports of a previous diagnosis of hypertension (yes, no) and their current blood pressure levels (hypertensive, normotensive).
Logistic regression analyses indicated that hypertensives who were unaware of their condition were significantly less likely to report chest pain than normotensives without a previous hypertension diagnosis; however, these groups did not differ in pain reports at other body sites. In contrast, both hypertensives and normotensives with a previous hypertension diagnosis were significantly more likely to report pain at several body sites as compared to normotensives without a previous hypertension diagnosis. It was also found that when hypertension awareness was held constant, resting systolic blood pressure was negatively associated with the likelihood of reporting chest and gallbladder pain.
These findings suggest that existing laboratory evidence of hypertension-related hypoalgesia may not translate to decreased daily pain symptoms, although there is intriguing evidence of dampened cardiac pain in hypertensives who are unaware of their condition.
在本研究中，我们调查了大量不同的男性和女性样本中高血压、疼痛报告与高血压知晓情况之间的关系。
对第三次全国健康与营养检查调查（NHANES III）期间收集的数据进行检查，分析了9427名成年人在四个身体部位（胸部、背部、腿部和胆囊）的疼痛报告。根据受访者之前高血压诊断的自我报告（是、否）以及他们当前的血压水平（高血压、血压正常）将其分为四组。
逻辑回归分析表明，未意识到自己患有高血压的高血压患者报告胸痛的可能性显著低于之前未被诊断为高血压的血压正常者；然而，这些组在其他身体部位的疼痛报告方面没有差异。相比之下，与之前未被诊断为高血压的血压正常者相比，之前被诊断为高血压的高血压患者和血压正常者在多个身体部位报告疼痛的可能性显著更高。研究还发现，当高血压知晓情况保持不变时，静息收缩压与报告胸部和胆囊疼痛的可能性呈负相关。
这些发现表明，尽管有有趣的证据表明未意识到自己病情的高血压患者的心脏疼痛有所减轻，但现有的与高血压相关的痛觉减退的实验室证据可能无法转化为日常疼痛症状的减轻。
