Gajek Jacek, Zyśko Dorota
Katedra i Klinika Kardiologii Akademii Medycznej we Wrocławiu.
Pol Merkur Lekarski. 2003 Apr;14(82):369-71.
Vasovagal syncope is defined as a reflex loss of consciousness related to reaction to various stimuli as orthostatic stress, pain or emotions connected with loss of muscle postural tone. The aetiology of this disorder is still unknown. The imbalance between the parts of autonomic nervous system and other homeostasis-related systems as renin-angiotensin-aldosterone system, peptides as endothelin, neuropeptide Y, vasopressin, adrenomedullin and cAMP, adenosine and AMP can play an important role in the development of vasovagal syncope. In the first part of the paper the authors describe the mechanisms involved in the development of vasovagal reaction, pathophysiology of the head-up tilt test and the role of autonomic nervous system.
血管迷走性晕厥被定义为与对各种刺激(如直立性应激、疼痛或与肌肉姿势张力丧失相关的情绪)的反应有关的反射性意识丧失。这种疾病的病因仍然不明。自主神经系统各部分与其他内稳态相关系统(如肾素 - 血管紧张素 - 醛固酮系统)之间的失衡,以及诸如内皮素、神经肽Y、血管加压素、肾上腺髓质素和环磷酸腺苷、腺苷和一磷酸腺苷等肽类,可能在血管迷走性晕厥的发生发展中起重要作用。在本文的第一部分,作者描述了血管迷走反应发生发展的机制、头高位倾斜试验的病理生理学以及自主神经系统的作用。