Morin Stephen F, Maiorana Andre, Koester Kimberly A, Sheon Nicolas M, Richards T Anne
AIDS Policy Research Center, University of California, San Francisco, CA 94105, USA.
J Acquir Immune Defic Syndr. 2003 Aug 1;33(4):513-20. doi: 10.1097/00126334-200308010-00013.
To better understand how community advisory boards (CABs) can be used to improve the quality of HIV prevention trials.
Data collected included descriptive and epidemiologic reports, ethnographic observations, and face-to-face semistructured qualitative interviews with 67 CAB and research team members. Interviews were coded for themes related to community-based consultation.
The study was conducted at 6 sites of the HIV Prevention Trials Network-Los Angeles, California; Birmingham, Alabama; Philadelphia, Pennsylvania; Harare, Zimbabwe; Lima, Peru; and Chiang Mai, Thailand.
Thirty-six CAB members and 31 research team members, identified with the assistance of research staff at each site, were recruited for interviews across the 6 sites.
Both "broad community" and "population-specific" models were identified as strategies for CABs to represent potential participants in HIV prevention trials. CABs viewed their role as a bridge between the research team and trial participants. CABs improved prevention clinical trials by assisting in protocol development, recruitment, and retention. In addition, CABs both identified and helped resolve ethical issues in clinical trials.
When given time to develop, CABs appear to be a good strategy for building partnerships between researchers and communities for collaborative research projects. This approach has the potential to build sustainable capacity to identify and address ethical issues in research as well as community needs.
更好地了解如何利用社区咨询委员会（CABs）来提高艾滋病预防试验的质量。
收集的数据包括描述性和流行病学报告、人种志观察，以及对67名社区咨询委员会和研究团队成员进行的面对面半结构化定性访谈。访谈针对与社区咨询相关的主题进行编码。
该研究在艾滋病预防试验网络的6个地点开展——加利福尼亚州洛杉矶；阿拉巴马州伯明翰；宾夕法尼亚州费城；津巴布韦哈拉雷；秘鲁利马；泰国清迈。
在每个地点研究人员的协助下，招募了36名社区咨询委员会成员和31名研究团队成员，在6个地点进行访谈。
“广泛社区”和“特定人群”模式均被确定为社区咨询委员会在艾滋病预防试验中代表潜在参与者的策略。社区咨询委员会将自身角色视为研究团队与试验参与者之间的桥梁。社区咨询委员会通过协助方案制定、招募和保留参与者，提高了预防临床试验水平。此外，社区咨询委员会还识别并帮助解决了临床试验中的伦理问题。
如果有时间发展，社区咨询委员会似乎是研究人员与社区之间就合作研究项目建立伙伴关系的良好策略。这种方法有潜力建立可持续的能力，以识别和解决研究中的伦理问题以及社区需求。
