Pascuzzi Robert M
Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana 46202-2859, USA.
Semin Neurol. 2003 Mar;23(1):83-8. doi: 10.1055/s-2003-40755.
Cholinesterase inhibitors (CEIs) have been known to improve strength in patients with myasthenia gravis (MG) since the 1930s, and have been used as a diagnostic test since the early 1950s. The following review summarizes the history of edrophonium usage in myasthenia gravis, reviews the literature with regard to the method of performing the edrophonium test, and discusses the available information regarding sensitivity and specificity of the test with respect to diagnosis of MG.
自20世纪30年代以来，人们就已知道胆碱酯酶抑制剂（CEIs）可改善重症肌无力（MG）患者的肌力，自20世纪50年代初起，胆碱酯酶抑制剂就被用作一种诊断测试。以下综述总结了依酚氯铵在重症肌无力中的应用历史，回顾了有关进行依酚氯铵试验方法的文献，并讨论了关于该试验在诊断重症肌无力方面的敏感性和特异性的现有信息。
