[球后视神经炎患者的游标视力特征]

Liu Quan, Li Shaozhen, Woo George, Tang Shibo

Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.

Yan Ke Xue Bao. 2003 Jun;19(2):104-6.

PURPOSE

To investigate the clinical characteristic of vernier acuity in retrobulbar neuritis patients.

METHODS

The vernier acuity test soft wear system was developed to detect the 15 cases (25 eyes) with retrobulbar neuritis patients. There were 8 eyes of 6 cases with acute retrobulbar neuritis and 17 eyes of 9 cases with chronic retrobulbar neuritis. Subjects' age ranged from 11 to 58 (mean = 25.87). There were 14 eyes of 7 cases male and 11 eyes of 8 cases female. The best visual acuity ranged from 0.05 to 0.7. Two fixed targets and a movable target are shown on the computer screen. The examine was asked to adjust the position of the central target and the relationship between it and align them by using a track-ball. The computer automatically records the deviations of distances between the movable target and the specific one, and computes the average threshold and its variance.

RESULTS

There was significant statistical difference in the vernier threshold and its variance between the normal subjects and patients with retrobulbar neuritis in acute stage or convalescence. The correlation coefficient between visual acuity and vernier acuity threshold was -0.88 in the patients with retrobulbar neuritis in acute stage of neuritis (P < 0.01). The correlation coefficient between visual acuity and threshold variance was -0.46(P < 0.05). In convalescence, with an improvement of the disease and the increase of visual acuity, the vernier acuity threshold decreased and the threshold variance reduced. The difference of threshold and its variance between acute stage and convalescence had statistical signification (P < 0.01). The correlation coefficients between visual acuity and vernier acuity threshold was -0.93 in convalescence (P < 0.01). The correlation coefficients between visual acuity and vernier threshold variance was -0.84(P < 0.01) in convalescence. No significant statistical difference was found in the correlation between the vernier threshold in acute stage and in convalescence (P = 0.261). No significant statistical difference was found in the correlation between visual acuity in acute stage and in convalescence (P = 0.11). The correlation coefficients between vernier threshold variance in acute stage and in convalescence was -0.67 (P < 0.01). There was statistical difference among the difference of threshold, visual acuity and standard deviation between acute stage and convalescence respectively (t-test, P < 0.01).

CONCLUSIONS

It is suggested that vernier acuity, which changed with the state of the disease, was one of the indexes to evaluate the visual function of patients with retrobulbar neuritis. It could be use as an observation index of supervising the change of patients' visual function and the reaction to medication and guiding medication.

目的

探讨球后视神经炎患者游标视力的临床特征。

方法

开发游标视力测试软件系统，检测15例（25只眼）球后视神经炎患者。其中急性球后视神经炎6例8只眼，慢性球后视神经炎9例17只眼。受试者年龄11至58岁（平均25.87岁）。男性7例14只眼，女性8例11只眼。最佳视力范围为0.05至0.7。计算机屏幕上显示两个固定目标和一个可移动目标。要求受检者使用轨迹球调整中央目标的位置并使其与特定目标对齐。计算机自动记录可移动目标与特定目标之间距离的偏差，并计算平均阈值及其方差。

结果

正常人与急性期或恢复期球后视神经炎患者的游标阈值及其方差存在显著统计学差异。神经炎急性期球后视神经炎患者的视力与游标视力阈值之间的相关系数为 -0.88（P < 0.01）。视力与阈值方差之间的相关系数为 -0.46（P < 0.05）。在恢复期，随着病情改善和视力提高，游标视力阈值降低，阈值方差减小。急性期与恢复期阈值及其方差的差异具有统计学意义（P < 0.01）。恢复期视力与游标视力阈值之间的相关系数为 -0.93（P < 0.01）。恢复期视力与游标阈值方差之间的相关系数为 -0.84（P < 0.01）。急性期与恢复期游标阈值之间的相关性无显著统计学差异（P = 0.261）。急性期与恢复期视力之间的相关性无显著统计学差异（P = 0.11）。急性期与恢复期游标阈值方差之间的相关系数为 -0.67（P < 0.01）。急性期与恢复期阈值、视力及标准差差异分别有统计学差异（t检验，P < 0.01）。