Akar Ziya, Tanriover Necmettin, Tuzgen Saffet, Kafadar Ali M, Kuday Cengiz
Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
Neurol Med Chir (Tokyo). 2003 Jun;43(6):275-80; discussion 281. doi: 10.2176/nmc.43.275.
Intracranial epidermoid tumors are rare, potentially curable, benign lesions that are sometimes associated with perioperative complications, and tend to recur if not completely removed. Histologically benign epidermoid tumors may also develop into highly malignant tumors. This study evaluated on 28 cases of intracranial epidermoid tumor treated over a 13-year period by radical resection with microneurosurgical techniques. The majority of patients underwent computed tomography and/or magnetic resonance imaging within the first 24 hours postoperatively to confirm the results of surgery. Radical surgical resection was achieved in 21 of the 28 cases, and there was no operative mortality. The most common postoperative complication was transient paresis of various cranial nerves. During a mean follow up of 6 years, only one tumor became malignant. Radical surgical resection should be the goal in treating these benign lesions, but if not possible, every effort should be made to minimize the amount of tumor tissue that remains.
颅内表皮样肿瘤是罕见的、具有潜在可治愈性的良性病变，有时与围手术期并发症相关，如果未完全切除则容易复发。组织学上良性的表皮样肿瘤也可能发展为高度恶性肿瘤。本研究评估了在13年期间采用显微神经外科技术根治性切除治疗的28例颅内表皮样肿瘤。大多数患者在术后24小时内接受计算机断层扫描和/或磁共振成像以确认手术结果。28例中有21例实现了根治性手术切除，且无手术死亡病例。最常见术后并发症是各种颅神经的短暂性麻痹。在平均6年的随访期间，只有1例肿瘤发生恶变。根治性手术切除应是治疗这些良性病变的目标，但如果无法实现，则应尽一切努力将残留的肿瘤组织量降至最低。
