Ing E B, Sullivan T J, Clarke M P, Buncic J R
Hospital for Sick Children, University of Toronto, Ontario, Canada.
J Pediatr Ophthalmol Strabismus. 1992 Nov-Dec;29(6):331-6. doi: 10.3928/0191-3913-19921101-03.
Fifty-four patients with oculomotor nerve palsy who presented over a 21-year period at our institution were reviewed retrospectively. There were 38 isolated third nerve lesions, and 16 with additional cranial nerve involvement. Eleven cases were congenital in origin, and 43 were acquired. Of the acquired group, 31 were traumatic, 7 infection-related, 3 attributed to migraine or other vascular causes, and 2 neoplastic. Average follow up was 36 months. The congenital lesions were predominantly right-sided; amblyopia, although common, responded well to treatment. Trauma and bacterial meningitis accounted for more cases of isolated oculomotor nerve palsy than seen in the previous literature. In distinct contrast to the adult population, no cases of diabetes, posterior communicating artery aneurysms, metastatic tumors, or pituitary lesions were found.
对在我们机构21年期间出现动眼神经麻痹的54例患者进行了回顾性研究。有38例孤立性第三神经病变，16例伴有其他颅神经受累。11例为先天性起源，43例为后天性。在后天性组中，31例为创伤性，7例与感染有关，3例归因于偏头痛或其他血管原因，2例为肿瘤性。平均随访36个月。先天性病变主要为右侧；弱视虽然常见，但对治疗反应良好。创伤和细菌性脑膜炎导致的孤立性动眼神经麻痹病例比以往文献报道的更多。与成人人群形成鲜明对比的是，未发现糖尿病、后交通动脉瘤、转移性肿瘤或垂体病变的病例。
