Wadhwa Raju P, Kozarek Richard A, France Renee E, Brandabur John J, Gluck Michael, Low Donald E, Traverso L William, Moonka Ravi
Section of Gastroenterology, Virginia Mason Medical Center, Seattle, Washington 98101, USA.
Gastrointest Endosc. 2003 Aug;58(2):207-12. doi: 10.1067/mge.2003.343.
The self-expandable metallic stent is of proven benefit in patients with malignant disease; however, its use in patients with benign disease is not well established. There are few data available regarding long-term complications and outcomes with use of self-expandable metallic stents in benign disease and virtually none regarding attempted removal once the acute problem is resolved.
Thirteen patients who had a self-expandable metallic stent placed for benign GI disorders were included in a retrospective analysis. Data collected included patient demographics, indication for procedure, type of stent used, complications, and patient outcomes.
Thirteen patients (7 women, 6 men; mean age 67 years, range 34-84 years) had one or more self-expandable metallic stents placed for benign disease and were followed for a mean of 3.4 years (3 weeks to 10 years). Of the 13 patients, 8 had esophageal stents, 4 biliary stents, and 1 had dual stents placed in the pancreaticobiliary tree. Complications developed in 8 (62%) patients; 4 (31%) ultimately died, either from the primary disease process (3) or from stent-related complications (1).
Self-expandable metallic stent placement is effective treatment for benign esophageal leaks, providing the stent can be removed. It also may be used in either the esophagus or biliary tree in patients who are poor candidates for surgery and short expected survival. However, a self-expandable metallic stent should not be placed in a patient with a benign GI disorder who has a significant life expectancy and is a good candidate for surgery.
自膨式金属支架已被证实对恶性疾病患者有益;然而,其在良性疾病患者中的应用尚未得到充分确立。关于自膨式金属支架在良性疾病中的长期并发症和结局的数据很少,而且一旦急性问题得到解决,关于尝试取出支架的数据几乎没有。
对13例因良性胃肠道疾病放置自膨式金属支架的患者进行回顾性分析。收集的数据包括患者人口统计学资料、手术指征、使用的支架类型、并发症和患者结局。
13例患者(7例女性,6例男性;平均年龄67岁,范围34 - 84岁)因良性疾病放置了一个或多个自膨式金属支架,平均随访3.4年(3周至10年)。13例患者中,8例放置了食管支架,4例放置了胆道支架,1例在胰胆管树中放置了双支架。8例(62%)患者出现并发症;4例(31%)最终死亡,其中3例死于原发性疾病,1例死于与支架相关的并发症。
自膨式金属支架置入术是治疗良性食管瘘的有效方法,前提是支架能够取出。它也可用于手术候选不佳且预期生存期短的食管或胆道疾病患者。然而,对于预期寿命长且手术候选良好的良性胃肠道疾病患者,不应放置自膨式金属支架。