Stoler Mark H
Robert E. Fechner Laboratory of Surgical Pathology, Department of Pathology, University of Virginia Health System, Charlottesville 22908, USA.
Arch Pathol Lab Med. 2003 Aug;127(8):935-9. doi: 10.5858/2003-127-935-HPBACN.
Human papillomaviruses are necessary for the development of cervical neoplasia. Progress in our understanding of the epithelial biology of this common pathogen has greatly influenced current concepts of cervical carcinogenesis. This understanding has provided a framework for understanding the biologic basis of many diagnostic criteria. Furthermore, classification schemes, diagnostic testing, and clinical management have been modified and clarified in light of this knowledge.
人乳头瘤病毒是宫颈肿瘤发生所必需的。我们对这种常见病原体上皮生物学的理解进展极大地影响了当前的宫颈癌发生概念。这种理解为理解许多诊断标准的生物学基础提供了一个框架。此外,鉴于这些知识,分类方案、诊断检测和临床管理都已得到修改和明确。