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人乳头瘤病毒生物学与宫颈肿瘤形成:对诊断标准和检测的影响

Human papillomavirus biology and cervical neoplasia: implications for diagnostic criteria and testing.

作者信息

Stoler Mark H

机构信息

Robert E. Fechner Laboratory of Surgical Pathology, Department of Pathology, University of Virginia Health System, Charlottesville 22908, USA.

出版信息

Arch Pathol Lab Med. 2003 Aug;127(8):935-9. doi: 10.5858/2003-127-935-HPBACN.

DOI:10.5858/2003-127-935-HPBACN
PMID:12873164
Abstract

Human papillomaviruses are necessary for the development of cervical neoplasia. Progress in our understanding of the epithelial biology of this common pathogen has greatly influenced current concepts of cervical carcinogenesis. This understanding has provided a framework for understanding the biologic basis of many diagnostic criteria. Furthermore, classification schemes, diagnostic testing, and clinical management have been modified and clarified in light of this knowledge.

摘要

人乳头瘤病毒是宫颈肿瘤发生所必需的。我们对这种常见病原体上皮生物学的理解进展极大地影响了当前的宫颈癌发生概念。这种理解为理解许多诊断标准的生物学基础提供了一个框架。此外,鉴于这些知识,分类方案、诊断检测和临床管理都已得到修改和明确。

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Human papillomavirus biology and cervical neoplasia: implications for diagnostic criteria and testing.人乳头瘤病毒生物学与宫颈肿瘤形成:对诊断标准和检测的影响
Arch Pathol Lab Med. 2003 Aug;127(8):935-9. doi: 10.5858/2003-127-935-HPBACN.
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Utility of P16/INK4a and Ki-67 in Preneoplasticand Neoplastic Lesions of Cervix.P16/INK4a和Ki-67在子宫颈癌前病变和肿瘤性病变中的应用
Iran J Pathol. 2018 Summer;13(3):308-316. Epub 2018 Sep 12.
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Biomarkers of cervical dysplasia and carcinoma.宫颈发育不良和癌的生物标志物。
J Oncol. 2012;2012:507286. doi: 10.1155/2012/507286. Epub 2011 Oct 29.
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Human papillomavirus (HPV) detection using in situ hybridization in histologic samples: correlations with cytologic changes and polymerase chain reaction HPV detection.原位杂交法检测组织学样本中的人乳头瘤病毒(HPV):与细胞学改变及聚合酶链反应 HPV 检测的相关性。
Am J Clin Pathol. 2011 Jul;136(1):119-27. doi: 10.1309/AJCP03HUQYZMWATP.
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Prophylactic human papillomavirus vaccines.预防性人乳头瘤病毒疫苗
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