Esikova T Z, Grishchenkov V G
Mikrobiologiia. 1992 Sep-Oct;61(5):843-51.
On the basis of the study of some Tn5 induced mutants in Pseudomonas putida strain BS836 containing the plasmid pBS268 coding caprolactam degradation, growth on caprolactam and its intermediates, and the data on the induction of oxidative activities in plasmid containing P. putida strain BS831 it was shown that plasmid and chromosome genes regulated the expression of CAP-determinants. The regulation has some elements of the negative control mechanism. Caprolactam is the inducer of the synthesis of key enzymes cleaving it and its intermediates (aminocaproic and adipic acids). At the same time each of its intermediates induced the synthesis of enzymes responsible for its cleavage.
在对恶臭假单胞菌菌株BS836中一些由Tn5诱导的突变体进行研究的基础上，该菌株含有编码己内酰胺降解的质粒pBS268，研究了其在己内酰胺及其中间体上的生长情况，以及含有恶臭假单胞菌菌株BS831的质粒中氧化活性诱导的数据，结果表明质粒和染色体基因调节了CAP决定簇的表达。这种调节具有负控机制的一些要素。己内酰胺是裂解它及其中间体（氨基己酸和己二酸）的关键酶合成的诱导物。同时，其每种中间体都诱导了负责其裂解的酶的合成。
