Lang J M, Oberling F, Juif J G, Luckel J C, Mayer S
Nouv Rev Fr Hematol. 1975 May-Jun;15(3):390-3.
The reactivity to PHA stimulation of peripheral blood lymphocytes from a child with a Chediak-Higashi syndrome was studied. Lymphocyte transformation was assayed by tritiated-thymidine incorporation. Patient lymphocytes reacted to much lower concentrations of PHA than normal controls. With an optimal dose of PHA the peak of thymidine uptake occurred on day 2 of incubation instead of day 4 as observed in normals.
对一名患有切-希二氏综合征儿童的外周血淋巴细胞对PHA刺激的反应性进行了研究。通过氚标记胸腺嘧啶核苷掺入法检测淋巴细胞转化。患者淋巴细胞对PHA的反应浓度远低于正常对照。使用最佳剂量的PHA时，胸腺嘧啶核苷摄取峰值出现在培养的第2天，而不是如正常人那样出现在第4天。
