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小鼠下丘频率调谐曲线形状的空间图谱。

Spatial map of frequency tuning-curve shapes in the mouse inferior colliculus.

作者信息

Ehret Günter, Egorova Marina, Hage Steffen R, Müller Birgit A

机构信息

Department of Neurobiology, University of Ulm, D-89069 Ulm, Germany.

出版信息

Neuroreport. 2003 Jul 18;14(10):1365-9. doi: 10.1097/01.wnr.0000078545.07662.85.

DOI:10.1097/01.wnr.0000078545.07662.85
PMID:12876475
Abstract

Neurons in the central nucleus of the auditory midbrain inferior colliculus divide into four classes according to the shapes of their receptive fields. Neurons of two of these classes - sharply tuned, inhibition-dominated neurons of class II, and broadly tuned neurons of class III - show systematic gradients in their abundance on isofrequency contours. Sharp tuning is most prevalent in the center, broad tuning in the periphery of the ICC. This new map of tuning-curve shape adds to the six previously described maps of neural response properties on isofrequency contours of the ICC and stresses the fact that very different sensitivities and selectivities to sound properties are combined in local clusters of collicular neurons.

摘要

听觉中脑下丘中央核中的神经元根据其感受野的形状分为四类。其中两类神经元——II类调谐尖锐、抑制主导的神经元和III类调谐宽泛的神经元——在等频率轮廓上的丰度呈现出系统梯度。尖锐调谐在ICC中心最为普遍,宽泛调谐在ICC周边最为普遍。这种调谐曲线形状的新图谱补充了之前描述的ICC等频率轮廓上的六种神经反应特性图谱,并强调了这样一个事实,即对声音特性非常不同的敏感性和选择性在丘神经元的局部簇中组合在一起。

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