Okubo Ken, Kiyohara Yutaka
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University.
Nihon Rinsho. 2003 Jul;61(7):1081-6.
It is well known that diabetes often induces macrovascular and microvascular complications, and hypertension is also considered to be an important risk factor for macrovascular events. Recent epidemiological studies have proved the possibility that hypertension among patients with diabetes greatly increases the risks of these complications. However, the impact of hypertension on stroke and microvascular complications is considered to be greater than that on coronary heart disease. Co-existent metabolic risk factors such as hyperlipidemia rather than hypertension may affect more coronary heart disease. Antihypertensive treatment among diabetic patients is expected to reduce various complications, but management of metabolic risk factors is also needed to prevent coronary heart disease.
众所周知，糖尿病常引发大血管和微血管并发症，高血压也被视为大血管事件的重要危险因素。近期的流行病学研究证实，糖尿病患者中的高血压会大幅增加这些并发症的风险。然而，高血压对中风和微血管并发症的影响被认为大于对冠心病的影响。并存的代谢危险因素如高脂血症而非高血压可能对冠心病影响更大。糖尿病患者的降压治疗有望减少各种并发症，但预防冠心病也需要对代谢危险因素进行管理。
