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替加环素(GAR-936)及其他12种抗菌药物对90株腐蚀艾肯菌临床分离株的体外活性

In vitro activities of tigecycline (GAR-936) and 12 other antimicrobial agents against 90 Eikenella corrodens clinical isolates.

作者信息

Cercenado Emilia, Cercenado Sonia, Bouza Emilio

机构信息

Servicio de Microbiología, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

出版信息

Antimicrob Agents Chemother. 2003 Aug;47(8):2644-5. doi: 10.1128/AAC.47.8.2644-2645.2003.

Abstract

The activity of tigecycline was compared with those of other antimicrobials against 90 isolates of Eikenella corrodens. The MIC at which 90% of the isolates were inhibited was 2 micro g/ml for tigecycline and 1, </=0.5/0.25, 0.5, </=0.12, </=2, and 0.5 micro g/ml for ampicillin, amoxicillin-clavulanate, cefotaxime, imipenem, chloramphenicol, and ciprofloxacin, respectively.

摘要

将替加环素与其他抗菌药物对90株腐蚀艾肯菌的活性进行了比较。替加环素对90%分离株产生抑制作用的最低抑菌浓度(MIC)为2μg/ml,氨苄西林、阿莫西林-克拉维酸、头孢噻肟、亚胺培南、氯霉素和环丙沙星的MIC分别为1、≤0.5/0.25、0.5、≤0.12、≤2和0.5μg/ml。

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