Cercenado Emilia, Cercenado Sonia, Bouza Emilio
Servicio de Microbiología, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Antimicrob Agents Chemother. 2003 Aug;47(8):2644-5. doi: 10.1128/AAC.47.8.2644-2645.2003.
The activity of tigecycline was compared with those of other antimicrobials against 90 isolates of Eikenella corrodens. The MIC at which 90% of the isolates were inhibited was 2 micro g/ml for tigecycline and 1, </=0.5/0.25, 0.5, </=0.12, </=2, and 0.5 micro g/ml for ampicillin, amoxicillin-clavulanate, cefotaxime, imipenem, chloramphenicol, and ciprofloxacin, respectively.
将替加环素与其他抗菌药物对90株腐蚀艾肯菌的活性进行了比较。替加环素对90%分离株产生抑制作用的最低抑菌浓度(MIC)为2μg/ml,氨苄西林、阿莫西林-克拉维酸、头孢噻肟、亚胺培南、氯霉素和环丙沙星的MIC分别为1、≤0.5/0.25、0.5、≤0.12、≤2和0.5μg/ml。