新型去氟喹诺酮类药物BMS 284756与其他七种抗菌药物对151株腐蚀艾肯菌的体外活性
In vitro activities of a new des-fluoroquinolone, BMS 284756, and seven other antimicrobial agents against 151 isolates of Eikenella corrodens.
作者信息
Goldstein Ellie J C, Citron Diane M, Merriam C Vreni, Warren Yumi A, Tyrrell Kerin L, Fernandez Helen
机构信息
The R. M. Alden Research Laboratory and UCLA Medical Center, Santa Monica, California 90404, USA.
出版信息
Antimicrob Agents Chemother. 2002 Apr;46(4):1141-3. doi: 10.1128/AAC.46.4.1141-1143.2002.
Abstract
The des-fluoroquinolone BMS 284756 was active in vitro against all 151 clinical strains of Eikenella corrodens at a MIC of < or = 0.25 microg/ml and was comparable in activity to moxifloxacin and levofloxacin. The MIC at which 90% of the isolates were inhibited by penicillin G was 2 microg/ml; MICs for 8.6% of the strains (13 of 151) were > or = 4 microg/ml, including for two beta-lactamase-producing isolates. Amoxicillin-clavulanate and ampicillin-sulbactam inhibited all strains at a MIC of < or = 1 microg/ml.
摘要
去氟喹诺酮BMS 284756在体外对151株啮蚀艾肯菌临床菌株均有活性，其最低抑菌浓度（MIC）≤0.25μg/ml，活性与莫西沙星和左氧氟沙星相当。青霉素G抑制90%分离株的MIC为2μg/ml；8.6%的菌株（151株中的13株）MIC≥4μg/ml，其中包括2株产β-内酰胺酶的分离株。阿莫西林-克拉维酸和氨苄西林-舒巴坦在MIC≤1μg/ml时可抑制所有菌株。
相似文献
1
In vitro activities of a new des-fluoroquinolone, BMS 284756, and seven other antimicrobial agents against 151 isolates of Eikenella corrodens.
Antimicrob Agents Chemother. 2002 Apr;46(4):1141-3. doi: 10.1128/AAC.46.4.1141-1143.2002.
2
In vitro activities of tigecycline (GAR-936) and 12 other antimicrobial agents against 90 Eikenella corrodens clinical isolates.
Antimicrob Agents Chemother. 2003 Aug;47(8):2644-5. doi: 10.1128/AAC.47.8.2644-2645.2003.
3
In vitro activities of BMS-284756 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae.
Antimicrob Agents Chemother. 2002 Feb;46(2):517-8. doi: 10.1128/AAC.46.2.517-518.2002.
4
Comparative antianaerobic activity of BMS 284756.
Antimicrob Agents Chemother. 2001 Feb;45(2):589-92. doi: 10.1128/AAC.45.2.589-592.2001.
5
Activities of BMS 284756 (T-3811) against Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae isolates from SENTRY antimicrobial surveillance program medical centers in Latin America (1999).
Antimicrob Agents Chemother. 2001 May;45(5):1463-6. doi: 10.1128/AAC.45.5.1463-1466.2001.
6
Activity and spectrum of BMS 284756, a new des-F (6) quinolone, tested against strains of ciprofloxacin-resistant Gram-positive cocci.
Diagn Microbiol Infect Dis. 2001 Feb;39(2):133-5. doi: 10.1016/s0732-8893(00)00233-9.
7
[Activity of 14 antimicrobials against Eikenella corrodens].
Rev Argent Microbiol. 2002 Oct-Dec;34(4):230-4.
8
Bactericidal activities of BMS-284756, a novel Des-F(6)-quinolone, against Staphylococcus aureus strains with topoisomerase mutations.
Antimicrob Agents Chemother. 2002 Jan;46(1):191-5. doi: 10.1128/AAC.46.1.191-195.2002.
9
Antibacterial spectrum of a novel des-fluoro(6) quinolone, BMS-284756.
Antimicrob Agents Chemother. 2000 Dec;44(12):3351-6. doi: 10.1128/AAC.44.12.3351-3356.2000.
10
Antipneumococcal activity of BMS 284756 compared to those of six other agents.
Antimicrob Agents Chemother. 2002 Jan;46(1):251-4. doi: 10.1128/AAC.46.1.251-254.2002.
引用本文的文献
1
Bacteremia caused by Eikenella corrodens in a patient with pelvic inflammatory disease.
Rev Esp Quimioter. 2023 Jun;36(3):329-331. doi: 10.37201/req/128.2022. Epub 2023 Mar 21.
2
Eikenella corrodens infections in human: Reports of six cases and review of literatures.
J Clin Lab Anal. 2022 Feb;36(2):e24230. doi: 10.1002/jcla.24230. Epub 2022 Jan 12.
3
In vitro activities of tigecycline (GAR-936) and 12 other antimicrobial agents against 90 Eikenella corrodens clinical isolates.
Antimicrob Agents Chemother. 2003 Aug;47(8):2644-5. doi: 10.1128/AAC.47.8.2644-2645.2003.
本文引用的文献
1
Trovafloxacin compared with levofloxacin, ofloxacin, ciprofloxacin, azithromycin and clarithromycin against unusual aerobic and anaerobic human and animal bite-wound pathogens.
J Antimicrob Chemother. 1998 Mar;41(3):391-6. doi: 10.1093/jac/41.3.391.
2
Comparative in vitro activities of trovafloxacin (CP-99,219) against 221 aerobic and 217 anaerobic bacteria isolated from patients with intra-abdominal infections.
Antimicrob Agents Chemother. 1997 Oct;41(10):2312-6. doi: 10.1128/AAC.41.10.2312.
3
In vitro activities of trovafloxacin against 557 strains of anaerobic bacteria.
Antimicrob Agents Chemother. 1996 Sep;40(9):2232-5. doi: 10.1128/AAC.40.9.2232.
4
Clonal diversity of oral Eikenella corrodens within individual subjects by arbitrarily primed PCR.
J Clin Microbiol. 1996 Jul;34(7):1837-9. doi: 10.1128/JCM.34.7.1837-1839.1996.
5
Cloning and sequencing of two type 4 (N-methylphenylalanine) pilin genes from Eikenella corrodens.
J Gen Microbiol. 1993 Mar;139(3):651-60. doi: 10.1099/00221287-139-3-651.
6
DNA probe detection of periodontopathogens in advanced periodontitis.
Scand J Dent Res. 1993 Dec;101(6):363-70. doi: 10.1111/j.1600-0722.1993.tb01133.x.
7
Isolation of Actinomyces species and Eikenella corrodens from patients with chronic diffuse sclerosing osteomyelitis.
J Oral Maxillofac Surg. 1994 Jan;52(1):26-33; discussion 33-4. doi: 10.1016/0278-2391(94)90008-6.
8
Susceptibility of Eikenella corrodens to newer beta-lactam antibiotics.
Antimicrob Agents Chemother. 1980 Nov;18(5):832-3. doi: 10.1128/AAC.18.5.832.
9
Pathogenicity of Eikenella corrodens in humans.
Arch Intern Med. 1983 Dec;143(12):2265-8.
10
Prevalence of Eikenella corrodens in dental plaque.
J Clin Microbiol. 1983 Apr;17(4):636-9. doi: 10.1128/jcm.17.4.636-639.1983.
Zotero 插件