Garel Catherine, Chantrel Emmanuel, Elmaleh Monique, Brisse Hervé, Sebag Guy
Department of Paediatric Imaging, Hôpital Robert Debré, 48 boulevard Sérurier, 75019 Paris, France.
Childs Nerv Syst. 2003 Aug;19(7-8):422-5. doi: 10.1007/s00381-003-0767-4. Epub 2003 Jul 16.
Up until the last 10 years, normal cerebral gestational landmarks were assessed by ultrasonographic and fetopathologic studies. The purpose of this paper is to display the possibilities provided by fetal MRI in the evaluation of fetal cerebral biometry, normal sulcation and myelination.
Two hundred and twenty-five fetuses (with a normal brain) were studied prospectively using a standardised method. The gestational age ranged from 22 to 38 weeks. The main data concerning biometry of various cerebral structures at those terms are given.
In contrast to ultrasound, MRI allows measurements of brain (and not skull), which are available independently of the position of the fetal head. The timing of the appearance of the different sulci is also available using MRI. It is considered to be a good marker of fetal brain maturation. The biochemical modifications contemporary to myelination make it possible to evaluate this phenomenon in the fetal brain using MRI.
直到过去十年，正常脑妊娠标志是通过超声检查和胎儿病理学研究来评估的。本文的目的是展示胎儿磁共振成像（MRI）在评估胎儿脑生物测量、正常脑沟形成和髓鞘形成方面所提供的可能性。
采用标准化方法对225例（脑正常）胎儿进行前瞻性研究。孕周范围为22至38周。给出了这些孕周时各种脑结构生物测量的主要数据。
与超声不同，MRI能够测量脑（而非颅骨），且测量结果不受胎儿头部位置的影响。利用MRI还可以确定不同脑沟出现的时间。它被认为是胎儿脑成熟的一个良好标志。髓鞘形成过程中伴随的生化改变使得利用MRI评估胎儿脑内的这一现象成为可能。
