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Fetal surgery for myelomeningocele.

作者信息

Sutton Leslie N, Adzick N Scott, Johnson Mark P

机构信息

Division of Neurosurgery, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19087, USA.

出版信息

Childs Nerv Syst. 2003 Aug;19(7-8):587-91. doi: 10.1007/s00381-003-0787-0. Epub 2003 Jul 15.

DOI:10.1007/s00381-003-0787-0
PMID:12879345
Abstract

INTRODUCTION

Although in utero treatment of myelomeningocele shows promise in decreasing the morbidity of this disease, the risks to the fetus are significant, and the benefits are unproven.

TRIAL

The upcoming trial represents one of the few times that the pediatric neurosurgical community has come together to test a new procedure.

摘要

相似文献

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Fetal surgery for myelomeningocele.
Childs Nerv Syst. 2003 Aug;19(7-8):587-91. doi: 10.1007/s00381-003-0787-0. Epub 2003 Jul 15.
2
A randomized trial of prenatal versus postnatal repair of myelomeningocele.随机试验:产前与产后修复脊髓脊膜膨出。
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N Engl J Med. 2002 Jul 25;347(4):256-9. doi: 10.1056/NEJMoa013325.
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Current controversies in prenatal diagnosis 3: fetal surgery after MOMS: is fetal therapy better than neonatal?产前诊断的当前争议3:MOMS研究后的胎儿手术:胎儿治疗是否优于新生儿治疗?
Prenat Diagn. 2013 Jan;33(1):13-6. doi: 10.1002/pd.4037.
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Reducing perinatal complications and preterm delivery for patients undergoing in utero closure of fetal myelomeningocele: further modifications to the multidisciplinary surgical technique.减少胎儿脊髓脊膜膨出宫内闭合术患者的围产期并发症和早产:多学科手术技术的进一步改进
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引用本文的文献

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Epidemiology, prenatal management, and prevention of neural tube defects.神经管缺陷的流行病学、产前管理及预防
Saudi Med J. 2014 Dec;35 Suppl 1(Suppl 1):S15-28.

本文引用的文献

1
Late gestational intrauterine myelomeningocele repair does not improve lower extremity function.孕晚期宫内脊髓脊膜膨出修复术不能改善下肢功能。
Pediatr Neurosurg. 2003 Mar;38(3):128-32. doi: 10.1159/000068818.
2
The effect of intrauterine myelomeningocele repair on the incidence of shunt-dependent hydrocephalus.宫内脊髓脊膜膨出修补术对分流依赖型脑积水发生率的影响。
Pediatr Neurosurg. 2003 Jan;38(1):27-33. doi: 10.1159/000067560.
3
Dermoid inclusion cysts and early spinal cord tethering after fetal surgery for myelomeningocele.
胎儿脊髓脊膜膨出修补术后的皮样包涵囊肿与早期脊髓栓系
N Engl J Med. 2002 Jul 25;347(4):256-9. doi: 10.1056/NEJMoa013325.
4
Prenatal diagnosis of terminal myelocystocele in the fetal surgery era: case report.
Neurosurgery. 2002 May;50(5):1152-4; discussion 1154-5. doi: 10.1097/00006123-200205000-00040.
5
In utero meconium exposure increases spinal cord necrosis in a rat model of myelomeningocele.在子宫内接触胎粪会增加脊髓脊膜膨出大鼠模型中的脊髓坏死。
J Pediatr Surg. 2002 Mar;37(3):488-92. doi: 10.1053/jpsu.2002.30872.
6
A new look at myelomeningoceles: functional level, vertebral level, shunting, and the implications for fetal intervention.脊髓脊膜膨出的新视角:功能水平、椎体水平、分流术及其对胎儿干预的影响
Pediatrics. 2002 Mar;109(3):409-13. doi: 10.1542/peds.109.3.409.
7
Can prenatal ultrasound findings predict ambulatory status in fetuses with open spina bifida?产前超声检查结果能否预测脊柱裂胎儿的活动状态?
Am J Obstet Gynecol. 2001 Nov;185(5):1016-20. doi: 10.1067/mob.2001.117676.
8
Hindbrain herniation develops in surgically created myelomeningocele but is absent after repair in fetal lambs.后脑疝出在手术制造的脊髓脊膜膨出中出现,但在胎羊修复后不存在。
Am J Obstet Gynecol. 2000 Nov;183(5):1119-23. doi: 10.1067/mob.2000.108867.
9
Fetal MRI in the evaluation of intrauterine myelomeningocele.胎儿磁共振成像在评估宫内脊髓脊膜膨出中的应用
Pediatr Neurosurg. 2000 Mar;32(3):124-31. doi: 10.1159/000028916.
10
Improvement in hindbrain herniation demonstrated by serial fetal magnetic resonance imaging following fetal surgery for myelomeningocele.胎儿脊髓脊膜膨出症手术治疗后,通过系列胎儿磁共振成像显示后颅窝疝有所改善。
JAMA. 1999 Nov 17;282(19):1826-31. doi: 10.1001/jama.282.19.1826.