Spinu I, Mihalcu F, Horhogea G, Debeleac L
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1975 Oct-Dec;20(4):213-8.
In order to find methods for the prevention and control of streptococcal infections of 711 day schoolchildren and boarders, aged 7 to 14 years, were followed up during the 1969-1973 period. The clinical and epidemiologic investigations revealed a great number of acute infections with varied clinical manifestations and high proportions of the acute articular rheumatism (3.1%) in the boarding schools as compared to the day schools (0.5%). The bacteriologic examinations confirmed and established the etiology of the cases, revealing moreover the role of carriers in maintaining and spreading the infection. The ASLO test showed persistent and high gammaglobulin titers in the children of the boarding schools, pointing to a state of hypersensitivity consequent to repeated streptococcal infections.
为了寻找711名7至14岁的日校学生和寄宿生链球菌感染的预防和控制方法,在1969年至1973年期间对他们进行了随访。临床和流行病学调查发现大量急性感染,临床表现各异,寄宿学校急性关节风湿热的比例(3.1%)高于日校(0.5%)。细菌学检查证实并确定了病例的病因,此外还揭示了带菌者在维持和传播感染中的作用。抗链球菌溶血素O试验显示寄宿学校儿童的γ球蛋白滴度持续且较高,表明反复链球菌感染导致了过敏状态。