Măgureanu E, Dobrescu A, Busuioc C, Ulmeanu V, Horhogea G, Ionescu M, Horhogea P, Beznea A
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1982 Jan-Mar;27(1):17-22.
In further investigations on the evolutive trends of the epidemiologic streptococcal process, an extensive epidemiological survey was carried out in prescholar and school communities in the town of Bucharest with a view to applying efficient antiepidemic measures able to limit primary streptococcal infections and prevent late, redoubtable complications. In 1980, in Bucharest, morbidity from scarlet fever was at its lowest level (92.7 per 100,000) during the last 31 years; it was in general benign, affecting especially in the month of March the 5-9 years age group (623.9 per 100,000) and the 1-4 years age group (529.4 per 100,000). The trailing evolution of a scarlet fever focus in a prescholar community suggested the hypothesis of the potentiation of the induction of streptococcal toxigenesis under the influence of intercurrent vital infections, especially measles. There were no deaths from scarlet fever. Laboratory investigations for the active detection and treatment of anginas, of carriers at risk, totalled 52101 tests; of these 4478 (8.59%) were positive for group "A" streptococci. In the prescholar communities surveyed no poststreptococcal complications were reported (acute articular rheumatism and glomerulonephritis). In 1980, there were 63 cases of acute articular rheumatism (code 250) in the 0-18 year-old group. The results suggest the need of continued epidemiological survey of streptococcal infections in children with a view to improving the health status of the population.
在对流行性链球菌感染过程的演变趋势进行进一步调查时，我们在布加勒斯特市的学龄前儿童社区和学校社区开展了广泛的流行病学调查，旨在采取有效的防疫措施，以限制原发性链球菌感染，并预防后期出现的严重并发症。1980年，布加勒斯特市的猩红热发病率处于过去31年中的最低水平（每10万人中92.7例）；总体病情较轻，尤其在3月份，主要影响5至9岁年龄组（每10万人中623.9例）和1至4岁年龄组（每10万人中529.4例）。在一个学龄前儿童社区中猩红热疫情的后续发展情况提示，在并发的严重感染（尤其是麻疹）影响下，链球菌产毒作用增强的假说成立。未出现猩红热死亡病例。为了积极检测和治疗咽峡炎以及有风险的带菌者，共进行了52101次实验室检测；其中4478例（8.59%）“A”组链球菌检测呈阳性。在所调查的学龄前儿童社区中，未报告有链球菌感染后的并发症（急性关节风湿热和肾小球肾炎）。1980年，0至18岁年龄组中有63例急性关节风湿热病例（编码250）。结果表明，有必要持续对儿童的链球菌感染进行流行病学调查，以改善人群的健康状况。
