二氢林德布拉迪酮，来自黏菌管形林德布拉迪菌的三种新萘醌色素。

Dihydrolindbladiones, three new naphthoquinone pigments from a myxomycete Lindbladia tubulina.

作者信息

Misono Yuka, Ishikawa Yae, Yamamoto Yukinori, Hayashi Masahiko, Komiyama Kanki, Ishibashi Masami

机构信息

Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.

出版信息

J Nat Prod. 2003 Jul;66(7):999-1001. doi: 10.1021/np030089x.

DOI:10.1021/np030089x

PMID:12880324

Abstract

Three new naphthoquinone pigments, 6,7-dimethoxydihydrolindbladione (1), dihydrolindbladione (2), and 6-methoxydihydrolindbladione (3), have been isolated from a myxomycete Lindbladia tubulina, and their structures were elucidated by spectral data. Compound 3 appreciably exhibited a reversal effect of multidrug resistance. Lindbladione (4), the major pigment of this myxomycete, was also isolated from Cribraria intricata.

摘要

从黏菌管形林氏菌（Lindbladia tubulina）中分离出了三种新的萘醌色素，即6,7-二甲氧基二氢林氏二酮（1）、二氢林氏二酮（2）和6-甲氧基二氢林氏二酮（3），并通过光谱数据阐明了它们的结构。化合物3明显表现出多药耐药的逆转作用。该黏菌的主要色素林氏二酮（4）也从交错筛菌（Cribraria intricata）中分离得到。