置有通气管的儿童咽鼓管功能的左右差异
Left-right differences in Eustachian tube function in children with ventilation tubes.
作者信息
van Heerbeek Niels, Akkerman Annemiek E, Ingels Koen J A O, Engel Joost A M, Zielhuis Gerhard A
机构信息
Department of Otorhinolaryngology, University Medical Center Nijmegen, Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, Netherlands.
出版信息
Int J Pediatr Otorhinolaryngol. 2003 Aug;67(8):861-6. doi: 10.1016/s0165-5876(03)00128-9.
OBJECTIVE
To study the intraindividual variation in Eustachian tube (ET) function in children with ventilation tubes.
METHODS
The forced response test, the pressure equilibration test and the sniff test were performed on both ears of 148 children. The results of both ears were compared.
RESULTS
No systematic differences were found between the left and the right ears. However, the intraindividual variation was very pronounced. The variation in passive ET function within children was of similar magnitude as the variation in passive ET function between children. Twenty-eight percent of the children had different active ET function in both ears and 15% had an opposite result in each ear with respect to the sniff test.
CONCLUSIONS
This study shows that ET function is much more a characteristic of the individual ear than of the individual child. These findings also question the validity of trials on ET function or middle ear disease that use the opposite ear as a control (split level design).
目的
研究置有通气管的儿童咽鼓管（ET）功能的个体内差异。
方法
对148名儿童的双耳进行强制反应试验、压力平衡试验和嗅气试验。比较双耳的结果。
结果
左右耳之间未发现系统性差异。然而，个体内差异非常显著。儿童被动ET功能的差异幅度与儿童之间被动ET功能的差异幅度相似。28%的儿童双耳的主动ET功能不同，15%的儿童在嗅气试验中双耳结果相反。
结论
本研究表明，ET功能更多地是个体耳朵的特征，而非个体儿童的特征。这些发现也质疑了以对侧耳朵作为对照（分层设计）的ET功能或中耳疾病试验的有效性。
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