Piiper J
Department of Physiology, Max Planck Institute for Experimental Medicine, Göttingen, F.R.G.
Adv Exp Med Biol. 1992;316:3-10. doi: 10.1007/978-1-4615-3404-4_1.
By injection of embolizing microspheres, by local radioactive xenon clearance and by inert gas washout in resting and stimulated gastrocnemius dog preparation, experimental evidence for unequal blood flow distribution and for shunt flow has been provided. Model calculations show that in some respect unequal blood flow and shunt produce effects predicted for a homogeneous model with diffusion limitation of O2 supply. This finding must be taken into account when the role of diffusion limitation to O2 supply is to be ascertained.
通过向犬腓肠肌制备物中注射栓塞微球、进行局部放射性氙清除以及在静息和刺激状态下进行惰性气体冲洗，已获得血流分布不均和分流存在的实验证据。模型计算表明，在某些方面，血流不均和分流产生的效应与具有氧气供应扩散限制的均匀模型所预测的效应相同。在确定氧气供应扩散限制的作用时，必须考虑这一发现。
