Pal'mina N P, Kledova L V, Pankova T V, Gaintseva V D
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 119991 Russia.
Radiats Biol Radioecol. 2003 May-Jun;43(3):310-4.
On the basis of antioxidant (alpha-tocopherol and phenosan potassium salt) and peptide (thyroliberin) effects on the lipid peroxide oxidation (LPO) and lipid structural parameters of the endoplasmic reticulum membranes in wide concentration range (10(-20)-10(-4) mol/l) in vitro the possibility concerning a proposed role of "super-affine" receptors in the mechanism of biologically active substances (BAS) action in ultra low doses (ULD) is discussed. Because these substances modulate investigated processes in the membranes which have not ordinarily receptors the conclusion about availability of non-receptor component in the mechanism of BAS effect in ULD and a low probability of "super-affine" receptor existence has been done.
基于抗氧化剂（α-生育酚和苯磺酸酸钾盐）和肽（促甲状腺素释放激素）在体外宽浓度范围（10⁻²⁰ - 10⁻⁴mol/L）对脂质过氧化（LPO）和内质网膜脂质结构参数的影响，讨论了关于“超亲和”受体在超低剂量（ULD）生物活性物质（BAS）作用机制中所提出作用的可能性。由于这些物质调节了通常没有受体的膜中的研究过程，得出了关于ULD中BAS作用机制中存在非受体成分以及“超亲和”受体存在可能性较低的结论。
