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[重组人促红细胞生成素对老年血液透析患者贫血的效用]

[Utility of recombinant human erythropoietin on the anemia of elderly hemodialysis patients].

作者信息

Ueyama H, Nakahashi H, Sawanishi K, Kuze M, Ono T

机构信息

Department of Urology, Kyoto City Hospital.

出版信息

Hinyokika Kiyo. 1992 Dec;38(12):1429-35.

PMID:1288237
Abstract

Recombinant human erythropoietin was administered to 59 patients over 65 years of age receiving maintenance hemodialysis treatment in Kyoto and Shiga district, in order to evaluate its utility on renal anemia. After 6 months of administration, the hematocrit rose from 20.8 +/- 3.5% to 28.0 +/- 3.7% with concomitant improvement of subjective symptoms related to anemia. Twelve patients developed side effects, in 10 of whom elevation of blood pressure was observed. We found no clinically significant abnormalities in the laboratory data. In conclusion, recombinant human erythropoietin is highly useful in the treatment of renal anemia in elderly hemodialysis patients.

摘要

为评估重组人促红细胞生成素对肾性贫血的疗效,在京都和滋贺地区对59例65岁以上接受维持性血液透析治疗的患者使用了该药物。给药6个月后,血细胞比容从20.8±3.5%升至28.0±3.7%,同时与贫血相关的主观症状有所改善。12例患者出现副作用,其中10例观察到血压升高。我们在实验室数据中未发现具有临床意义的异常情况。总之,重组人促红细胞生成素对老年血液透析患者的肾性贫血治疗非常有用。

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