Maddison J E
Department of Pharmacology, University of Sydney, New South Wales.
Aust Vet J. 1992 Nov;69(11):288-91. doi: 10.1111/j.1751-0813.1992.tb09896.x.
Fifty-nine reports of suspected adverse drug reactions (ADRs) were received by the Adverse Drug Reaction Subcommittee of the Australian Veterinary Association from February 1991-March 1992 inclusive. The number of reports received/number of animals involved per species was: dogs (23/24); cats (20/30); horses (4/4); cattle (7/10); sheep (3/745); poultry (1/580); pigs (1/8). Of these, 38 (64%) were classified as definite ADRs and 9 (15%) as probable ADRs. In 10 (17%) reports an ADR could not be substantiated or there was insufficient information available to make a decision. Two reports involved veterinarians inadvertently overdosing animals. Eighteen reports involved apparent hypersensitivity reactions and 6 reports involved probable drug interactions. Four reports involved the use of drugs at appropriate doses but in inappropriate clinical situations, and 3 reports were associated with 'off-label' use.
1991年2月至1992年3月（含）期间，澳大利亚兽医协会药物不良反应小组委员会共收到59份疑似药物不良反应（ADR）报告。按物种统计，收到的报告数量/涉及的动物数量分别为：犬（23/24）；猫（20/30）；马（4/4）；牛（7/10）；羊（3/745）；家禽（1/580）；猪（1/8）。其中，38份（64%）被归类为确诊的ADR，9份（15%）为很可能的ADR。10份报告（17%）中，ADR无法得到证实，或者没有足够信息做出判断。两份报告涉及兽医意外给动物过量用药。18份报告涉及明显的过敏反应，6份报告涉及可能的药物相互作用。4份报告涉及在适当剂量但不适当的临床情况下使用药物，3份报告与“超适应症”使用有关。
