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动脉导管未闭经导管弹簧圈栓塞术后声带麻痹

Vocal cord paralysis after transcatheter coil embolization of patent ductus arteriosus.

作者信息

Liang Chi Di, Ko Sheung Fat, Huang Song Chei, Huang Chien Fu, Niu Chen Kuan

机构信息

Department of Pediatrics, Chang Gung Children's Hospital, Kaohsiung, Taiwan.

出版信息

Am Heart J. 2003 Aug;146(2):367-71. doi: 10.1016/S0002-8703(03)00125-X.

Abstract

BACKGROUND

In patients with patent ductus arteriosus (PDA) after Gianturco coil embolization, vocal cord paralysis (VCP) had not been previously described. This study investigates the risk factors of coil embolization associated with VCP.

METHODS

We reviewed the medical records of all patients who had undergone transcatheter closure of PDA with a Gianturco coil between March 1998 and May 2001, and 75 patients (age range, 6 months to 55 years; mean age, 5.5 years) were identified. The procedure was performed with local anesthesia and with sedation in some young children. No patient required general anesthesia or endotracheal intubation.

RESULTS

Three of the 75 patients had hoarseness caused by VCP after coil embolization. Patients with VCP had a longer ductus length (P <.01) and a smaller ductus diameter (P <.01) than patients without VCP. The pathogenesis of VCP may be caused by tense stretching and angulation of the ductus arteriosus induced by the implanted coil, which leads to compression injury of the adjacent left recurrent laryngeal nerve.

CONCLUSIONS

A long ductus length (> or =12 mm) and a small ductus diameter (<1 mm) are significant risk factors of VCP after coil embolization in children <1 year of age. We recommend that coil embolization be performed very carefully in patients with PDA.

摘要

背景

在使用弹簧圈栓塞治疗动脉导管未闭(PDA)的患者中,此前尚未有关于声带麻痹(VCP)的报道。本研究调查与VCP相关的弹簧圈栓塞危险因素。

方法

我们回顾了1998年3月至2001年5月期间所有使用弹簧圈经导管闭合PDA的患者的病历,共确定了75例患者(年龄范围6个月至55岁;平均年龄5.5岁)。该操作在局部麻醉下进行,部分幼儿同时给予镇静。无一例患者需要全身麻醉或气管插管。

结果

75例患者中有3例在弹簧圈栓塞后出现了由VCP导致的声音嘶哑。与无VCP的患者相比,VCP患者的动脉导管长度更长(P<.01)且动脉导管直径更小(P<.01)。VCP的发病机制可能是由于植入的弹簧圈导致动脉导管紧张拉伸和成角,进而引起邻近左喉返神经的压迫损伤。

结论

对于1岁以下儿童,动脉导管长度较长(≥12 mm)和动脉导管直径较小(<1 mm)是弹簧圈栓塞后发生VCP的重要危险因素。我们建议对PDA患者进行弹簧圈栓塞时应非常谨慎。

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