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注意缺陷多动障碍的“成熟滞后”假说:最新进展

"Maturational lag" hypothesis of attention deficit hyperactivity disorder: an update.

作者信息

El-Sayed E, Larsson J O, Persson H E, Santosh P J, Rydelius P A

机构信息

Department of Woman and Child Health, Child and Adolescent Psychiatric Unit, Karolinska Institutet, Astrid Lindgren Children's Hospital, Karolinska Hospital, Stockholm, Sweden.

出版信息

Acta Paediatr. 2003 Jul;92(7):776-84.

Abstract

UNLABELLED

This article discusses the relationship of maturation to ADHD and hyperkinetic disorder (HKD), with an emphasis on current research in ADHD and HKD, persistence and remission of ADHD symptoms over time and brain maturational trajectories.

CONCLUSION

ADHD is a broad, heterogeneous syndrome and only a subgroup of subjects has a diagnosis of HKD, which is a subset of individuals with severe ADHD combined subtype. Children showing symptoms above the threshold for a diagnosis of ADHD are at risk of developing comorbid conditions and increasing stress in both parents and teachers. In some subjects, ADHD symptoms can improve over time during maturation and development. These children with a diagnosis of ADHD could be viewed as showing variants of normal childhood behaviour with maturational trajectories that are lagging behind but will catch up. ADHD could therefore represent a continuum from normality at one extreme to a severe disorder, HKD according to ICD-10, at the other extreme.

摘要

未标注

本文讨论成熟与注意力缺陷多动障碍(ADHD)及多动障碍(HKD)的关系,重点关注ADHD和HKD的当前研究、ADHD症状随时间的持续性和缓解情况以及大脑成熟轨迹。

结论

ADHD是一种广泛的、异质性综合征,只有一部分受试者被诊断为HKD,HKD是重度ADHD合并型个体的一个子集。表现出高于ADHD诊断阈值症状的儿童有发生共病的风险,会给家长和教师带来越来越大的压力。在一些受试者中,ADHD症状在成熟和发育过程中会随时间改善。这些被诊断为ADHD的儿童可被视为表现出正常童年行为的变体,其成熟轨迹滞后但会赶上。因此,ADHD可能代表了从一端的正常到另一端根据国际疾病分类第10版(ICD - 10)定义的重度障碍HKD的一个连续体。

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