内吞膜运输与分选过程中的脂质

Lipids in endocytic membrane transport and sorting.

作者信息

Gruenberg Jean

机构信息

Department of Biochemistry, University of Geneva, 30 quai Ernest Ansermet, 1211 4, Geneva, Switzerland.

出版信息

Curr Opin Cell Biol. 2003 Aug;15(4):382-8. doi: 10.1016/s0955-0674(03)00078-4.

DOI:10.1016/s0955-0674(03)00078-4

PMID:12892777

Abstract

Protein complexes associated to specific membrane lipids and protein-lipid domains contribute to regulate protein sorting and membrane dynamics in the endocytic pathway. It is also becoming apparent that different lipid territories are distributed along the pathway, and that some lipids segregate into specialised microdomains.

摘要

与特定膜脂和蛋白质-脂质结构域相关的蛋白质复合物有助于调节内吞途径中的蛋白质分选和膜动力学。越来越明显的是，不同的脂质区域沿着该途径分布，并且一些脂质会分离成特殊的微结构域。