Carney Robert M, Freedland Kenneth E
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63108, USA.
Biol Psychiatry. 2003 Aug 1;54(3):241-7. doi: 10.1016/s0006-3223(03)00111-2.
There is substantial evidence that depression is a risk factor for cardiac morbidity and mortality, both for patients without clinical evidence of coronary heart disease at index examination and for patients with established coronary disease. The relationship is most apparent for patients with a recent acute myocardial infarction. Many questions about the impact of depression on heart disease remain unresolved.
有大量证据表明，抑郁症是心脏发病和死亡的危险因素，无论是在首次检查时无冠心病临床证据的患者，还是已确诊冠心病的患者。这种关系在近期发生急性心肌梗死的患者中最为明显。关于抑郁症对心脏病影响的许多问题仍未得到解决。
