Albani Justin M, Novick Andrew C
Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Urology. 2003 Aug;62(2):227-31. doi: 10.1016/s0090-4295(03)00364-9.
To report 3 cases of renal artery pseudoaneurysm (RAP) after partial nephrectomy and review the literature to discuss their unique presentation, clinical course, and management. RAPs are a rare clinical entity. They are a well-documented source of hemorrhage in association with renal biopsy, renal trauma, renal transplant, and percutaneous procedures; however, little is known about their presentation, pathophysiology, and management after nephron-sparing surgery.
Between 2000 and 2002, 698 partial nephrectomies were performed at our institution for treatment of suspected localized renal malignancy. A retrospective review of these cases revealed that 3 patients developed a postoperative RAP. These cases were reviewed along with the current medical literature available from the MEDLINE database to characterize this clinical entity further.
Three patients developed RAP after 698 uncomplicated partial nephrectomies were performed (0.43% incidence). Illustrating a classic presentation, the patient in case 1 was successfully treated with selective embolization after presenting with symptoms 3 weeks postoperatively. The patient in case 2 was treated with elective partial selective embolization for an asymptomatic lesion that later resolved spontaneously. In case 3, the patient presented early during the hospital course and required urgent selective embolization.
RAP after nephron-sparing surgery is a rare, but potentially life-threatening, condition that is often difficult to diagnose and requires a high index of suspicion. Treatment should be tailored to each patient's clinical presentation to minimize morbidity and maximize renal conservation. All urologists should be aware of this potential postoperative complication and prepare accordingly.
报告3例部分肾切除术后肾动脉假性动脉瘤(RAP)病例,并回顾文献以探讨其独特表现、临床病程及处理方法。RAP是一种罕见的临床病症。在肾活检、肾外伤、肾移植及经皮操作中,它们是有充分文献记载的出血来源;然而,对于其在保留肾单位手术后的表现、病理生理学及处理方法却知之甚少。
2000年至2002年间,我们机构为治疗疑似局限性肾恶性肿瘤进行了698例部分肾切除术。对这些病例进行回顾性分析发现,3例患者术后发生了RAP。结合MEDLINE数据库中的现有医学文献对这些病例进行分析,以进一步明确这一临床病症。
在698例无并发症的部分肾切除术后,有3例患者发生了RAP(发生率为0.43%)。病例1的患者术后3周出现症状,经选择性栓塞成功治疗,体现了典型表现。病例2的患者因无症状性病变接受了选择性部分栓塞治疗,该病变后来自行消退。病例3的患者在住院期间早期出现症状,需要紧急进行选择性栓塞。
保留肾单位手术后的RAP是一种罕见但可能危及生命的病症,通常难以诊断,需要高度怀疑。治疗应根据每位患者的临床表现进行调整,以尽量减少发病率并最大限度地保留肾功能。所有泌尿外科医生都应意识到这种潜在的术后并发症并做好相应准备。