Cağlayan Fatma, Cakmak Murat, Cağlayan Osman, Cavuşoglu Turgut
Department of Pediatric Surgery, Medical Faculty, Kirikkale University, Kirikkale, Turkey.
J Invest Surg. 2003 Jul-Aug;16(4):233-7.
We investigated the possible use of D-lactate as a predictor in the diagnosis of appendicitis. C-reactive protein level (CRP) and leukocyte counts were also evaluated. Venous blood D-lactate, CRP, and leukocyte counts were measured preoperatively in 53 patients undergoing surgery for appendicitis, as well as in 20 healthy subjects. Levels of all three parameters in the surgical patients were significantly higher than in the control group (p <.05). Previous studies have shown that venous D-lactate is more specific to the intestine than CPR or leukocyte count. Based on our data, venous D-lactate, which had the lowest false-negative rate among these laboratory parameters, may be a useful diagnostic marker for appendicitis. None of these parameters were helpful in identifying the type of the appendicitis.
我们研究了D-乳酸作为阑尾炎诊断预测指标的可能性。同时还评估了C反应蛋白水平（CRP）和白细胞计数。对53例接受阑尾炎手术的患者以及20名健康受试者在术前测定了静脉血D-乳酸、CRP和白细胞计数。手术患者的所有这三项参数水平均显著高于对照组（p<.05）。先前的研究表明，静脉血D-乳酸对肠道的特异性高于CPR或白细胞计数。根据我们的数据，在这些实验室参数中假阴性率最低的静脉血D-乳酸可能是阑尾炎的一个有用诊断标志物。这些参数均无助于确定阑尾炎的类型。
