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High mobility group box protein-1 (HMGB-1) as a new diagnostic marker in patients with acute appendicitis.高迁移率族蛋白 B1(HMGB-1)作为急性阑尾炎患者的新型诊断标志物。
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2
Diagnostic value of lactate levels in acute appendicitis.乳酸水平在急性阑尾炎中的诊断价值。
J Pak Med Assoc. 2010 Nov;60(11):913-5.
3
Diagnosing pediatric appendicitis: usefulness of laboratory markers.诊断小儿阑尾炎:实验室标志物的作用。
Am J Emerg Med. 2010 Nov;28(9):1009-15. doi: 10.1016/j.ajem.2009.06.004. Epub 2010 Mar 9.
4
The role of d-lactate in differential diagnosis of acute appendicitis.
J Invest Surg. 2010 Aug;23(4):218-23. doi: 10.3109/08941931003596877.
5
S100A8/A9: a potential new diagnostic aid for acute appendicitis.S100A8/A9:急性阑尾炎的潜在新诊断辅助手段。
Acad Emerg Med. 2010 Mar;17(3):333-6. doi: 10.1111/j.1553-2712.2010.00663.x.
6
C-reactive protein is superior to bilirubin for anticipation of perforation in acute appendicitis.在预测急性阑尾炎穿孔方面,C反应蛋白比胆红素更具优势。
Scand J Gastroenterol. 2010 Aug;45(7-8):885-92. doi: 10.3109/00365521003728572.
7
A prospective bicenter study investigating the diagnostic value of procalcitonin in patients with acute appendicitis.一项前瞻性双中心研究,旨在探讨降钙素原在急性阑尾炎患者中的诊断价值。
Eur Surg Res. 2009;43(3):291-7. doi: 10.1159/000232939. Epub 2009 Aug 7.
8
Bacterial translocation and change in intestinal permeability in patients after abdominal surgery.腹部手术后患者的细菌移位及肠道通透性变化
J Huazhong Univ Sci Technolog Med Sci. 2009 Aug;29(4):486-91. doi: 10.1007/s11596-009-0419-3. Epub 2009 Aug 7.
9
Discovery and validation of urine markers of acute pediatric appendicitis using high-accuracy mass spectrometry.利用高精度质谱法发现和验证急性小儿阑尾炎的尿液标志物。
Ann Emerg Med. 2010 Jan;55(1):62-70.e4. doi: 10.1016/j.annemergmed.2009.04.020. Epub 2009 Jun 25.
10
EXPERIMENTAL PROOF OF THE OBSTRUCTIVE ORIGIN OF APPENDICITIS IN MAN.人类阑尾炎梗阻性起源的实验证据。
Ann Surg. 1939 Oct;110(4):629-47. doi: 10.1097/00000658-193910000-00011.

血浆d-乳酸水平在急性阑尾炎中的预测作用综述:是谬论还是事实?

A review of the predictive role of plasma d-lactate level in acute appendicitis: a myth or truth?

作者信息

Unverir Pinar, Karcioglu Ozgur

机构信息

Department of Emergency Medicine, Ozel Ege Saglik Hospital, Universal Hospitals Group, Alsancak, 35220 Izmir, Turkey.

出版信息

ISRN Toxicol. 2011 Oct 12;2011:702372. doi: 10.5402/2011/702372. Print 2011.

DOI:10.5402/2011/702372
PMID:23724288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3658566/
Abstract

Acute appendicitis (AA) is a common condition which warrants emergency surgery. Detailed history, physical exam, and laboratory findings are often nonspecific in suspected patients. There is substantial evidence to indicate that plasma levels of D-lactate were useful to establish a diagnosis of AA in the medical literature. It has been suggested that it is useful for patients with abdominal pain, especially patients with perforated AA. This paper is designed to highlight the value of D-lactate biomarker in establishing a diagnosis of AA. Based on the literature, it is not helpful for a decision of operation in patients with AA. According to the results of the studies, laboratory involvement was observed between plasma D-lactate level and the final diagnosis of AA, particularly in perforated appendices. It can be considered for routine use in patients with undifferentiated abdominal pain in the emergency department setting.

摘要

急性阑尾炎(AA)是一种需要紧急手术的常见病症。详细的病史、体格检查和实验室检查结果在疑似患者中往往不具有特异性。有大量证据表明,在医学文献中,血浆D-乳酸水平有助于AA的诊断。有人提出,它对腹痛患者,尤其是穿孔性AA患者有用。本文旨在强调D-乳酸生物标志物在AA诊断中的价值。根据文献,它对AA患者的手术决策并无帮助。根据研究结果,观察到血浆D-乳酸水平与AA的最终诊断之间存在实验室关联,尤其是在阑尾穿孔的情况下。在急诊科,对于未分化腹痛患者可考虑将其作为常规检查项目。