Uddin S N, Siddiqui N I, Begum F, Malik F, Rahman S
Cardiology, Mymensingh Medical College, Bangladesh.
Mymensingh Med J. 2003 Jul;12(2):85-8.
Hundred patients of Type 2 diabetes mellitus with coronary artery disease undergoing diagnostic coronary angiography were studied to determine the relation between the severity and duration of diabetes mellitus and the severity of coronary artery disease. A coronary scoring system using segmental distribution method was used to determine the severity of coronary artery disease and severity of diabetes was assessed by the level of fasting blood glucose within 48 hours of the procedure and also considering the types of treatment received for diabetes mellitus. No significant correlation was demonstrated between the severity of coronary artery disease and the severity (r =.089602; P>0.1) nor the duration (r =0.07865; P> 0.1) of diabetes mellitus on univariate analysis. So the Type 2 diabetic patients had an increased incidence of atherosclerosis in their coronary angiograms did not reflect an angiographically evident progressive coronary artery disease and results of this study suggest that the progress of large vessel coronary athesclerotic disease in diabetes mellitus of adult onset takes place independently of the progress of diabetes mellitus itself.
对100例患有冠状动脉疾病的2型糖尿病患者进行诊断性冠状动脉造影，以确定糖尿病的严重程度和病程与冠状动脉疾病严重程度之间的关系。采用节段分布法的冠状动脉评分系统来确定冠状动脉疾病的严重程度，糖尿病的严重程度通过手术48小时内的空腹血糖水平以及所接受的糖尿病治疗类型来评估。单因素分析显示，冠状动脉疾病的严重程度与糖尿病的严重程度（r = 0.089602；P>0.1）和病程（r = 0.07865；P>0.1）均无显著相关性。因此，2型糖尿病患者冠状动脉造影中动脉粥样硬化发生率增加并不反映血管造影上明显的进行性冠状动脉疾病，本研究结果表明，成年起病型糖尿病中冠状动脉大血管粥样硬化疾病的进展独立于糖尿病本身的进展。
