Krishnaswami S, Joseph G, Punnoose E, Chandy S T
Dept of Cardiology, Christian Medical College Hospital, Vellore, Tamilnadu.
J Assoc Physicians India. 1996 Mar;44(3):169-71.
A study of 516 patients with diabetes mellitus who presented with chest pain and an equal number of matched controls without diabetes examined by selective coronary arteriography was undertaken. Detailed analysis of the angiograms showed that prevalence of CAD in diabetics with symptoms was 86.6%. This prevalence increased with age. Multivessel disease was more common in diabetics that in controls (p < 0.01). In diabetic patients disease involvement of proximal and distal segments in the same vessel was more common (p < 0.01). The Gensini score of quantitative expression of severity of CAD was higher in diabetics (p < 0.05). The number of occluded segments in the coronary tree was higher in diabetics (p < 0.01). No correlation could be established between severity of disease and age, body mass index or duration of diabetes. It is concluded that diabetes affects the coronary arteries of Indian patients more adversely than those of non-diabetics. The prevalence of CAD among diabetics increases linearly with age.
对516例出现胸痛症状的糖尿病患者以及同等数量经选择性冠状动脉造影检查的配对非糖尿病对照者进行了一项研究。血管造影的详细分析显示，有症状的糖尿病患者中冠心病的患病率为86.6%。该患病率随年龄增长而增加。多支血管病变在糖尿病患者中比在对照者中更常见（p<0.01）。在糖尿病患者中，同一血管的近端和远端节段受累更常见（p<0.01）。糖尿病患者中冠心病严重程度定量表达的Gensini评分更高（p<0.05）。糖尿病患者冠状动脉树中闭塞节段的数量更多（p<0.01）。疾病严重程度与年龄、体重指数或糖尿病病程之间未发现相关性。得出的结论是，糖尿病对印度患者冠状动脉的影响比对非糖尿病患者更不利。糖尿病患者中冠心病的患病率随年龄呈线性增加。
