Erler W, Kahlau D, Martin G, Naumann L, Schimmel D, Weber A
Bundesforschungsanstalt für Viruskrankheiten der Tiere, Standort Jena.
Berl Munch Tierarztl Wochenschr. 2003 Jul-Aug;116(7-8):288-92.
Mycobacterial strains from different outbreaks of tuberculosis of cattle in Germany from 1996 to 2001 were differentiated by two molecular biological methods (Spoligotyping, RFLP IS6110). The causative agent was in one case Mycobacterium (M.) africanum, in 10 cases M. bovis and in 17 cases M. bovis ssp. caprae, respectively. The results of the molecular biological methods are discussed from the perspective of epizootiology and the particular importance of infections by M. bovis ssp. caprae emphasized. Direct contact of the animals, purchase from infected stocks, infected zoo animals and wildlife, as well as livestock handlers are discussed as possible sources of infection.
采用两种分子生物学方法(间隔寡核苷酸分型、IS6110 限制性片段长度多态性分析)对 1996 年至 2001 年德国不同牛结核病疫情爆发中的分枝杆菌菌株进行了鉴别。病原体在 1 例中为非洲分枝杆菌,10 例中为牛分枝杆菌,17 例中分别为牛分枝杆菌山羊亚种。从动物流行病学角度讨论了分子生物学方法的结果,并强调了牛分枝杆菌山羊亚种感染的特殊重要性。还讨论了动物直接接触、从感染畜群购买、感染的动物园动物和野生动物以及家畜饲养员作为可能的感染源。