恶性黑色素瘤的I-123异丁基苄胍（IMP）与Ga-67枸橼酸盐闪烁扫描术的比较。

Comparison of I-123 IMP and Ga-67 citrate scintigraphy of malignant melanoma.

作者信息

Murata Katsuhito, Suzuki Kenichiro, Ayakawa Yoshio, Higashi Naoki, Paul Lin Pei-Jan

机构信息

Department of Radiology, Aichi Medical University, Nagoya, Japan.

出版信息

Clin Nucl Med. 2003 Aug;28(8):704-8. doi: 10.1097/01.RLU.0000079437.53206.be.

DOI:10.1097/01.RLU.0000079437.53206.be

PMID:12897669

Abstract

I-123 iodoamphetamine (IMP) and Ga-67 scintigraphy of malignant melanoma were performed to compare the accumulation of these tracers regarding tumor diameter to determine the site of I-123 IMP accumulation and to evaluate the use of I-123 IMP and Ga-67 in postoperative follow-up. The studies involved 44 patients with a definite diagnosis of malignant melanoma during a 10-year period from April 1991 through March 2001. In this study a very high detection rate of 90.9% was obtained for primary foci with I-123 IMP. With Ga-67, the primary site detection rate was 25%. The results suggest that I-123 IMP is superior to Ga-67 with respect to the detection rate of primary site.

摘要

对恶性黑色素瘤进行了I-123碘安非他明（IMP）和Ga-67闪烁扫描，以比较这些示踪剂在肿瘤直径方面的积聚情况，确定I-123 IMP的积聚部位，并评估I-123 IMP和Ga-67在术后随访中的应用。该研究纳入了1991年4月至2001年3月这10年间确诊为恶性黑色素瘤的44例患者。在本研究中，I-123 IMP对原发性病灶的检测率高达90.9%。使用Ga-67时，原发部位检测率为25%。结果表明，在原发性部位的检测率方面，I-123 IMP优于Ga-67。