对淀粉样蛋白的攻击
Attack on amyloid.
作者信息
Kahle Philipp J, De Strooper Bart
机构信息
Department of Biochemistry, Ludwig Maximilians University, Munich, Germany.
出版信息
EMBO Rep. 2003 Aug;4(8):747-51. doi: 10.1038/sj.embor.embor905. Epub 2003 Jul 25.
Abstract
International Titisee Conference on Alzheimer's and Parkinson's Disease: From Basic Science to Therapeutic Treatment
摘要
国际蒂蒂湖阿尔茨海默病与帕金森病会议
从基础科学到治疗方法
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本文引用的文献
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2
Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease.抗β-淀粉样蛋白抗体可减缓阿尔茨海默病的认知衰退。
Neuron. 2003 May 22;38(4):547-54. doi: 10.1016/s0896-6273(03)00294-0.
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Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2.γ-分泌酶是一种膜蛋白复合物，由早老素、尼卡斯特林、Aph-1和Pen-2组成。
Proc Natl Acad Sci U S A. 2003 May 27;100(11):6382-7. doi: 10.1073/pnas.1037392100. Epub 2003 May 9.
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Initiation and synergistic fibrillization of tau and alpha-synuclein.tau蛋白与α-突触核蛋白的起始及协同纤维化
Science. 2003 Apr 25;300(5619):636-40. doi: 10.1126/science.1082324.
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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex.Aph-1、Pen-2和Nicastrin与早老素生成一种活性γ-分泌酶复合物。
Neuron. 2003 Apr 10;38(1):9-12. doi: 10.1016/s0896-6273(03)00205-8.
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Reconstitution of gamma-secretase activity.γ-分泌酶活性的重建。
Nat Cell Biol. 2003 May;5(5):486-8. doi: 10.1038/ncb960.
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The role of presenilin cofactors in the gamma-secretase complex.早老素辅因子在γ-分泌酶复合物中的作用。
Nature. 2003 Mar 27;422(6930):438-41. doi: 10.1038/nature01506. Epub 2003 Mar 16.
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