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桡骨远端骨折患者未来骨折风险因素的识别。

Identification of risk factors for future fracture in patients following distal forearm fracture.

作者信息

Mulherin D, Williams S, Smith J A, Edwards J, Sheeran T P, Price T

机构信息

Department of Rheumatology, Cannock Chase Hospital, Brunswick Road, WS11 2XY Cannock, Staffordshire, United Kingdom.

出版信息

Osteoporos Int. 2003 Sep;14(9):757-60. doi: 10.1007/s00198-003-1441-0. Epub 2003 Jul 25.

Abstract

The challenge for healthcare systems around the world is delivering timely preventative strategies to subjects most likely to develop fragility fractures. The success or failure of national campaigns will be determined at local level, and many studies to date have found under-utilization of osteoporosis treatment strategies due to reduced public and healthcare professional awareness. An important link between the at-risk patients and their appropriate therapy is their identification and assessment. In the context of a medium sized secondary care provider, this study examined the efficiency of a nurse-led service for assessing women following distal forearm fracture, looking for additional risk factors for future fracture and also looking at uptake of the assessment programme among the target population. Two hundred and two women, median (range) age 69 (50-91) years presented with distal forearm fracture over a 9-month period. Fifty-four subjects did not participate in the study: they were significantly older than those who did ( P<0.002). One hundred and forty-eight subjects underwent assessment of falls risk, future hip fracture risk and calcaneal ultrasound attenuation measurement: 107 attended for assessment at the hospital and 41 required a health professional to visit at their place of residence-the latter group were significantly older ( P<0.0002). Of 148 subjects assessed, 76 (51%) had one or more risk factors for a fall: these subjects were significantly older ( P<0.0002) and more likely to have required a home visit ( P<0.002). Twenty-seven (18%) were considered at risk of a future hip fracture: again they were older and more likely to have required a home visit ( P<0.0005). Ninety-one subjects (61%) had a calcaneal ultrasound attenuation T-score below -2.0, and were referred for bone densitometry: again, they were older ( P<0.0002) and more likely to have required a home visit ( P<0.05). Bone densitometry demonstrated osteoporosis in 47 (52%) of those with low attenuation, osteopenia in 31 and normal bone density in 13. Of 76 subjects deemed to be at risk of falls, 31 (41%) had osteoporosis demonstrated on bone densitometry and of those at risk of future hip fracture, 12 (44%) had osteoporosis. Only nine (22%) subjects who received home visits had no risk factors for falls or hip fracture and normal bone density, compared to 45 (42%) of those who attended hospital. This study has demonstrated that the efficiency of a program to assess additional risk of future fracture in a population who have already fractured may be influenced by where the assessment is delivered: it may be that the patients at greatest risk did not avail of the service.

摘要

全球医疗保健系统面临的挑战是,为最有可能发生脆性骨折的人群提供及时的预防策略。国家层面运动的成败将在地方层面决定,而且迄今为止许多研究发现,由于公众和医疗保健专业人员的意识降低,骨质疏松症治疗策略的利用率较低。高危患者与其适当治疗之间的一个重要联系是对他们的识别和评估。在一家中等规模的二级医疗服务机构的背景下,本研究考察了由护士主导的一项服务在评估桡骨远端骨折后女性患者方面的效率,寻找未来骨折的其他风险因素,并观察目标人群对该评估项目的接受情况。在9个月的时间里,202名女性(年龄中位数[范围]为69[50 - 91]岁)因桡骨远端骨折前来就诊。54名受试者未参与研究:他们的年龄显著高于参与研究的受试者(P<0.002)。148名受试者接受了跌倒风险、未来髋部骨折风险和跟骨超声衰减测量的评估:107人在医院接受评估,41人需要医护人员到其住所进行访视——后一组年龄显著更大(P<0.0002)。在接受评估的148名受试者中,76名(51%)有一个或多个跌倒风险因素:这些受试者年龄显著更大(P<0.0002),并且更有可能需要上门访视(P<0.002)。27名(18%)被认为有未来髋部骨折风险:同样,他们年龄更大,更有可能需要上门访视(P<0.0005)。91名受试者(61%)的跟骨超声衰减T值低于 -2.0,并被转诊进行骨密度测定:同样,他们年龄更大(P<0.0002),更有可能需要上门访视(P<0.05)。骨密度测定显示,在超声衰减低的受试者中,47名(52%)患有骨质疏松症,31名患有骨质减少,13名骨密度正常。在76名被认为有跌倒风险的受试者中,31名(41%)在骨密度测定中显示患有骨质疏松症,在有未来髋部骨折风险的受试者中,12名(44%)患有骨质疏松症。与到医院就诊的受试者中的45名(42%)相比,仅9名(22%)接受上门访视的受试者没有跌倒或髋部骨折风险因素且骨密度正常。本研究表明,对于已经发生骨折的人群,评估未来骨折额外风险的项目的效率可能会受到评估地点 的影响:可能风险最大的患者没有利用这项服务。

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