Redman Leanne M, Scroop Garry C, Norman Robert J
Department of Physiology, University of Adelaide, 5005, Australia.
Eur J Appl Physiol. 2003 Nov;90(5-6):505-13. doi: 10.1007/s00421-003-0889-0. Epub 2003 Jul 26.
The purpose of the present study was to compare exercise status during the follicular (FP) and luteal (LP) phases of the menstrual cycle of a single group of young, sedentary women, where the marked differential in the blood concentrations of 17beta-oestradiol ([E(2)]) and progesterone ([P(4)]) has the potential to alter the metabolic response to exercise. Fourteen females [21.8 (4.0) years, peak oxygen uptake ( VO(2peak)) <45 ml x kg (-1) x min(-1)] performed both incremental exercise to exhaustion and steady-state submaximal cycle ergometer exercise while measurements were made of several metabolic and hormonal variables. With the incremental exercise test, time to exhaustion, maximal power output and total work done were not different between the two phases, nor were the absolute values for VO(2peak) or the corresponding values for ventilation ( VE), respiratory frequency ( f(R)) and heart rate (HR). Resting, end-exercise and peak (post-exercise) plasma lactate concentrations and the lactate threshold were not different between the two phases either. However, as the workloads increased during the incremental protocol, plasma lactate concentration, carbon dioxide output ( VCO(2)) and the respiratory exchange ratio (RER) all were lower during LP, while oxygen uptake ( VO(2)) was higher. With steady-state submaximal exercise, at workloads corresponding to 25% and 75% of menstrual cycle phase-specific VO(2peak), VO(2) and the oxygen pulse ( VO(2)/HR) were higher and RER and plasma lactate concentration lower during LP. Regardless of phase, [E(2)] increased with both incremental and steady-state submaximal exercise, while [P(4)] was unchanged. It is concluded that while exercise capacity, as defined by VO(2peak) and the lactate threshold, is unaffected by cycle phase in young, sedentary women, the metabolic responses in the LP during both incremental and steady-state submaximal exercise suggest a greater dependence on fat as an energy source.
本研究的目的是比较一组年轻、久坐不动女性在月经周期卵泡期（FP）和黄体期（LP）的运动状态，其中17β-雌二醇（[E(2)]）和孕酮（[P(4)]）的血液浓度存在显著差异，这有可能改变运动的代谢反应。14名女性[21.8（4.0）岁，峰值摄氧量（VO(2peak)）<45 ml·kg(-1)·min(-1)]进行了递增运动至疲劳和稳态次最大强度的自行车测力计运动，同时测量了几个代谢和激素变量。在递增运动试验中，疲劳时间、最大功率输出和总功在两个阶段之间没有差异，VO(2peak)的绝对值或通气（VE）、呼吸频率（f(R)）和心率（HR）的相应值也没有差异。两个阶段的静息、运动结束时和峰值（运动后）血浆乳酸浓度以及乳酸阈值也没有差异。然而，在递增运动方案中，随着工作量的增加，LP期间血浆乳酸浓度、二氧化碳排出量（VCO(2)）和呼吸交换率（RER）均较低，而摄氧量（VO(2)）较高。在稳态次最大强度运动中，在对应于月经周期阶段特异性VO(2peak)的25%和75%的工作量下，LP期间VO(2)和氧脉搏（VO(2)/HR）较高，RER和血浆乳酸浓度较低。无论处于哪个阶段，[E(2)]在递增运动和稳态次最大强度运动中均升高，而[P(4)]保持不变。结论是，虽然以VO(2peak)和乳酸阈值定义的运动能力在年轻、久坐不动的女性中不受月经周期阶段的影响，但在递增运动和稳态次最大强度运动期间，LP中的代谢反应表明对脂肪作为能量来源的依赖性更大。
