Sansone Randy A, Sansone Lori A
Department of Psychiatry, Wright State University School of Medicine, Dayton, Ohio, USA.
Int J Eat Disord. 2003 Sep;34(2):265-8. doi: 10.1002/eat.10181.
This paper describes the case of a 19-year-old female with anorexia nervosa (restricting type) who was prescribed metoclopramide (Reglan, Robins, Richmond, VA) for delayed gastric emptying. She subsequently experienced dramatic and unintended weight gain.
The initial treatment of delayed gastric emptying with metoclopramide did not result in a significant change in body weight. However, an increase in the dose resulted in a 20% increase in the patient's body weight over a 2-month period.
The risks of weight gain that accompany the administration of metoclopramide are discussed, as well as the postulated etiology and psychological implications for the patient.
本文描述了一名19岁神经性厌食症（限制型）女性患者的病例，该患者因胃排空延迟而服用了甲氧氯普胺（胃复安，罗宾斯公司，弗吉尼亚州里士满）。她随后意外出现了显著的体重增加。
最初用甲氧氯普胺治疗胃排空延迟并未导致体重显著变化。然而，剂量增加导致患者体重在2个月内增加了20%。
探讨了服用甲氧氯普胺伴随的体重增加风险，以及推测的病因和对患者的心理影响。
