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甲氧氯普胺对神经性厌食症患者胃排空的影响

Metoclopramide-induced gastric emptying in patients with anorexia nervosa.

作者信息

Saleh J W, Lebwohl P

出版信息

Am J Gastroenterol. 1980 Aug;74(2):127-32.

PMID:7446514
Abstract

Study of gastric retention of 99mTc-labeled meal by gamma camera is a reliable technic. Patients with anorexia nervosa were found to have increased gastric retention or delayed gastric emptying of a standard meal. Administration of metoclopramide acutely enhanced gastric emptying and chronically improved the weight and gastrointestinal symptoms of patients with anorexia nervosa. The gastrointestinal symptoms most significantly improved were: intolerance to meals, postprandial epigastric pain, belching, vomiting, anorexia and early satiety. Metoclopramide should be considered as an adjunct treatment in patients with anorexia nervosa.

摘要

用γ相机研究99mTc标记餐的胃潴留情况是一种可靠的技术。发现神经性厌食症患者对标准餐的胃潴留增加或胃排空延迟。急性给予甲氧氯普胺可促进胃排空,长期使用可改善神经性厌食症患者的体重和胃肠道症状。改善最显著的胃肠道症状包括:进食不耐受、餐后上腹部疼痛、嗳气、呕吐、厌食和早饱。甲氧氯普胺应被视为神经性厌食症患者的辅助治疗药物。

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