Ye P, Wang J, Shang Y, Zhu P
Division of Geriatric Cardiology, Chinese PLA General Hospital, Beijing 100853.
Chin Med Sci J. 2001 Mar;16(1):15-8.
To investigate the association of carotid arterial intima-media thickness (IMT) with principal cardiovascular risk factors in the elderly.
Carotid arterial IMT was measured by high resolution B mode ultrasound in 94 elderly subjects (old-aged group), and compared with subjects aged < 60 (middle-aged group).
In comparison with the middle-aged group, the prevalence of coronary heart disease, cerebral vascular disease, hypertension and diabetes mellitus was significantly higher, and serum cholesterol and systolic blood pressure were also significantly higher in old-aged group. Although there was no obvious difference in IMT between the two groups, carotid plaque and carotid wall thickening were more frequently found in old-aged group. Age, systolic blood pressure and serum cholesterol were shown as the independent determinants for carotid IMT in the total participants, whereas no such independent relation was found in old-aged group.
Age is the major risk factor for carotid atherosclerosis in the elderly. In other words, the occurrence of carotid atherosclerosis is the result of advancing age combined with the effect of multiple cardiovascular risk factors.
探讨老年人颈动脉内膜中层厚度（IMT）与主要心血管危险因素之间的关联。
采用高分辨率B型超声测量94例老年受试者（老年组）的颈动脉IMT，并与年龄<60岁的受试者（中年组）进行比较。
与中年组相比，老年组冠心病、脑血管疾病、高血压和糖尿病的患病率显著更高，血清胆固醇和收缩压也显著更高。虽然两组间IMT无明显差异，但老年组颈动脉斑块和颈动脉壁增厚更为常见。年龄、收缩压和血清胆固醇是所有参与者颈动脉IMT的独立决定因素，而老年组未发现此类独立关系。
年龄是老年人颈动脉粥样硬化的主要危险因素。换句话说，颈动脉粥样硬化的发生是年龄增长与多种心血管危险因素作用共同导致的结果。
