Drolsum Liv
Department of Ophthalmology, Hospital of Buskerud, Drammen, Norway.
J Cataract Refract Surg. 2003 Jul;29(7):1378-84. doi: 10.1016/s0886-3350(03)00013-0.
To evaluate the outcomes of conversion from trabeculectomy to deep sclerectomy with placement of a drainage implant.
Department of Ophthalmology, Hospital of Buskerud, Drammen, Norway.
Deep sclerectomy was performed in 41 patients (44 eyes) from November 1999 to January 2002. An absorbable implant (AquaFlow((R)), Staar Surgical) and a nonabsorbable implant (T.Flux((R)), IOLTech Laboratories) were used in 75% and 25% of eyes, respectively. Patients with open-angle glaucoma who needed filtering surgery were enrolled consecutively in a prospective study. Patients with 2 or more previous filtering surgeries or neovascular glaucoma were excluded, as were children. Of the original 48 eyes, accidental perforation of the trabeculo-Descemet's membrane occurred in 8.3%; these eyes were excluded from the study. The severity of optic nerve damage was considered in the decision to start therapy. An intraocular pressure (IOP) above 22 mm Hg was always treated.
After a mean follow-up of 12.9 months +/- 7.1 (SD), 61.4% of eyes were controlled without therapy. When eyes with previous surgery were excluded, the rate increased to 66.7% after a mean follow-up of 13.8 +/- 7.2 months. The mean IOP preoperatively and after 12 months was 27.9 +/- 6.9 mm Hg and 14.6 +/- 3.5 mm Hg, respectively (P<.001). The mean number of medications decreased from 3.4 +/- 1.0 preoperatively to 0.6 +/- 1.1 12 months postoperatively (P<.001). A reoperation was required in 2 cases (4.5%). There were no complications related to hypotony or other significant complications.
This study shows that conversion from trabeculectomy to deep sclerectomy with placement of an implant is safe. The postoperative IOP reduction was acceptable, and no significant complications occurred.
评估小梁切除术转换为带引流植入物的深层巩膜切除术的效果。
挪威德拉门布斯克鲁德医院眼科。
1999年11月至2002年1月,对41例患者(44只眼)实施了深层巩膜切除术。分别有75%和25%的眼使用了可吸收植入物(AquaFlow((R)),STAAR Surgical公司)和不可吸收植入物(T.Flux((R)),IOLTech Laboratories公司)。需要滤过手术的开角型青光眼患者连续纳入一项前瞻性研究。排除曾接受过2次或更多次滤过手术的患者、新生血管性青光眼患者以及儿童。在最初的48只眼中,小梁-Descemet膜意外穿孔的发生率为8.3%;这些眼被排除在研究之外。开始治疗的决策考虑了视神经损伤的严重程度。眼压高于22 mmHg时均进行治疗。
平均随访12.9个月±7.1(标准差)后,61.4%的眼无需治疗眼压得到控制。排除曾接受过手术的眼后,平均随访13.8±7.2个月,该比例增至66.7%。术前和术后12个月的平均眼压分别为27.9±6.9 mmHg和14.6±3.5 mmHg(P<0.001)。平均用药数量从术前的3.4±1.0降至术后12个月的0.6±1.1(P<0.001)。2例(4.5%)需要再次手术。未发生与低眼压相关的并发症或其他严重并发症。
本研究表明,小梁切除术转换为带植入物的深层巩膜切除术是安全的。术后眼压降低情况可接受,未发生严重并发症。