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抗青光眼植入手术的现代概念

Modern concepts in antiglaucomatous implant surgery.

作者信息

Dietlein T S, Jordan J, Lueke C, Krieglstein G K

机构信息

Department of Ophthalmology, University of Cologne, Joseph-Stelzmann-Str. 9, D-50931, Köln, Germany.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2008 Dec;246(12):1653-64. doi: 10.1007/s00417-008-0899-z. Epub 2008 Aug 6.

Abstract

BACKGROUND

Antiglaucomatous implant surgery is a continously evolving field in glaucoma treatment.

METHODS

A literature search with the terms "glaucoma implant surgery", "aqueous shunts" and "glaucoma drainage devices" was carried out, especially giving prominence to innovative surgical developments in glaucoma implant surgery and to recently established clinical evidence on traditional shunt surgery.

RESULTS

Episcleral glaucoma drainage devices have recently proven their efficacy in large studies. Longterm data about their clinical efficacy and their risk/safety profile are sufficiently available. New antiglaucomatous devices try to target alternative drainage routes, for example trabecular or uveoscleral outflow. Valid longterm data from prospective randomized clinical trials are not available for these devices as yet.

CONCLUSIONS

Although valid data on clinical application of the new glaucoma implants are not available as yet, profound knowledge about their theoretical concept and their practical management is obligatory for all glaucoma clinicians.

摘要

背景

抗青光眼植入手术是青光眼治疗中一个不断发展的领域。

方法

进行了一次文献检索,检索词为“青光眼植入手术”“房水引流装置”和“青光眼引流装置”,尤其突出了青光眼植入手术中的创新性手术进展以及近期关于传统分流手术的确立临床证据。

结果

巩膜外青光眼引流装置最近在大型研究中证明了其有效性。关于其临床疗效及其风险/安全性概况的长期数据已有充分可得。新型抗青光眼装置试图针对替代引流途径,例如小梁或葡萄膜巩膜外流。目前这些装置尚无来自前瞻性随机临床试验的有效长期数据。

结论

尽管关于新型青光眼植入物临床应用的有效数据目前尚无,但所有青光眼临床医生都必须深入了解其理论概念及其实际管理。

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