Mader Reuven
Rheumatic Diseases Unit, HaEmek Medical Center, Afula, Israel.
Isr Med Assoc J. 2003 Jul;5(7):506-8.
Diffuse idiopathic skeletal hyperostosis is often incorporated into osteoarthritis. Although DISH often coexists with OA, patients affected by this disorder differ from patients with primary OA in several aspects: prevalence in the general population, gender distribution, anatomic site of primary involvement, magnitude and distribution in the spine and the peripheral joints. DISH is a distinct clinical entity. Its recognition as such should stimulate clinicians and researchers to focus on its pathogenesis, treatment and prevention.
弥漫性特发性骨肥厚常被纳入骨关节炎范畴。尽管弥漫性特发性骨肥厚常与骨关节炎共存,但受该疾病影响的患者在几个方面与原发性骨关节炎患者有所不同:在普通人群中的患病率、性别分布、主要受累的解剖部位、在脊柱和外周关节中的程度及分布。弥漫性特发性骨肥厚是一种独特的临床实体。对其如此认定应促使临床医生和研究人员关注其发病机制、治疗和预防。