Jaklitsch Michael T, Mery Carlos M, Audisio Riccardo A
Division of Thoracic Surgery, Brigham and Women's Hospital, MA 02115, USA.
Lancet Oncol. 2003 Aug;4(8):463-71. doi: 10.1016/s1470-2045(03)01165-3.
Lung cancer is a leading cause of cancer death and its cure depends on an adequate surgical approach. More than half of all lung cancers are diagnosed in patients aged 65 years or over. However, surgical risk increases in patients over 65 years old. Therefore, surgical procedures for lung cancer are far less frequent in elderly patients. Many clinicians avoid surgery, or minimise surgical procedures on the basis of age but recent advances in preoperative risk assessment and surgical and anaesthetic techniques have resulted in a significant decrease in operative mortality and morbidity for older patients. The treatment of lung cancer in elderly patients should no longer be based on the premise that surgery is too risky for elderly patients. Every effort should be made to assess risk and optimise treatment for this large and expanding proportion of the population.
肺癌是癌症死亡的主要原因，其治愈取决于适当的手术方法。超过一半的肺癌患者在65岁及以上被诊断出来。然而，65岁以上患者的手术风险会增加。因此，老年患者中肺癌的手术治疗频率要低得多。许多临床医生基于年龄而避免手术或尽量减少手术操作，但术前风险评估以及手术和麻醉技术的最新进展已使老年患者的手术死亡率和发病率显著降低。老年患者肺癌的治疗不应再基于手术对老年患者风险太大这一前提。应尽一切努力评估风险并优化对这一庞大且不断扩大的人群的治疗。
